Evidence map›Paper›PMID 26520712›Full record

ArticleMedical physics2015

A minimum spanning forest based classification method for dedicated breast CT images.

Robert Pike, Ioannis Sechopoulos, Baowei Fei

Abstract readEvaluation StudyValidation Study
In one paragraph

Article in Medical physics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Dosimetry in x-ray-based breast imaging.Physics in medicine and biology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert PikeDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia 30329.
Ioannis SechopoulosDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia 30329 and Winship Cancer Institute of Emory University, Atlanta, Georgia 30322.
Baowei FeiDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia 30329; Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia 30322; Department of Mathematics and Computer Science, Emory University, Atlanta, Georgia 30322; and Winship Cancer Institute of Emory University, Atlanta, Georgia 30322.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
TARGETING DEATH RECEPTOR-MEDIATED APOPTOSIS FOR HEAD AND NECK CANCERP50CA128613 · NCI · EMORY UNIVERSITY · PI SHIN, DONG M · 2007 to 2011
$12.0M
uPAR Targeted in Vivo Molecular Magnetic Resonance Imaging of....P50CA128301 · NCI · EMORY UNIVERSITY · PI NYE, JONATHON A · 2008 to 2012
$6.8M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
Image Quality Improvement and Breast Compression Reduction in Breast TomosynthesiR01CA163746 · NCI · RADBOUD UNIVERSITY NIJMEGEN MED CTR · PI SECHOPOULOS, IOANNIS · 2012 to 2015
$1.2M
Targeted fusion biopsy using anti-[18F]FACBC PET/CT and real-time 3D ultrasound gR21CA176684 · NCI · EMORY UNIVERSITY · PI FEI, BAOWEI, MASTER, VIRAJ · 2013 to 2014
$568k
NCI NIH HHS P50 CA128301NCI NIH HHS P50CA128301NCI NIH HHS P50 CA128613NCI NIH HHS P50CA128613NCI NIH HHS R01 CA156775NCI NIH HHS R01CA156775NCI NIH HHS R01 CA163746NCI NIH HHS R01CA163746NCI NIH HHS R21 CA176684NCI NIH HHS R21CA176684NCRR NIH HHS UL1 RR025008
6 · The paper itself

Abstract

purposeTo develop and test an automated algorithm to classify different types of tissue in dedicated breast CT images.

methodsImages of a single breast of five different patients were acquired with a dedicated breast CT clinical prototype. The breast CT images were processed by a multiscale bilateral filter to reduce noise while keeping edge information and were corrected to overcome cupping artifacts. As skin and glandular tissue have similar CT values on breast CT images, morphologic processing is used to identify the skin based on its position information. A support vector machine (SVM) is trained and the resulting model used to create a pixelwise classification map of fat and glandular tissue. By combining the results of the skin mask with the SVM results, the breast tissue is classified as skin, fat, and glandular tissue. This map is then used to identify markers for a minimum spanning forest that is grown to segment the image using spatial and intensity information. To evaluate the authors' classification method, they use DICE overlap ratios to compare the results of the automated classification to those obtained by manual segmentation on five patient images.

resultsComparison between the automatic and the manual segmentation shows that the minimum spanning forest based classification method was able to successfully classify dedicated breast CT image with average DICE ratios of 96.9%, 89.8%, and 89.5% for fat, glandular, and skin tissue, respectively.

conclusionsA 2D minimum spanning forest based classification method was proposed and evaluated for classifying the fat, skin, and glandular tissue in dedicated breast CT images. The classification method can be used for dense breast tissue quantification, radiation dose assessment, and other applications in breast imaging.

Indexed as

AlgorithmsBreast NeoplasmsComputer SimulationFemaleHumansImaging, Three-DimensionalMammographyModels, StatisticalPattern Recognition, AutomatedRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray Computed

Identifiers

PMID26520712
PMCPMC4600081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.