Evidence map›Paper›PMID 26520656›Full record

ArticlePediatric surgery international2016

Comprehensive assessment of prognosis after laparoscopic portoenterostomy for biliary atresia.

Hiroki Nakamura, Hiroyuki Koga, Joel Cazares, Tadaharu Okazaki, Geoffrey J Lane, Go Miyano, Manabu Okawada, Takashi Doi, Masahiko Urao, Atsuyuki Yamataka

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Article in Pediatric surgery international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroki NakamuraDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Hiroyuki KogaDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Joel CazaresDepartment of Pediatric Surgery, Hospital Regional de Alta Especialidad Materno Infantil, Monterrey, Mexico.
Tadaharu OkazakiDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Geoffrey J LaneDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Go MiyanoDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Manabu OkawadaDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Takashi DoiDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Masahiko UraoDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Atsuyuki YamatakaDepartment of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan. yama@juntendo.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTotal bilirubin (T-bil) is used universally for monitoring post-portoenterostomy (PE) biliary atresia (BA) patients although other biochemical markers [BM; AST/ALT and platelet count (PC)] are also prognostic. We compared open PE (OPE) with laparoscopic PE (LPE) using T-bil, AST/ALT, and PC (3BM) as more comprehensive indicators of postoperative clinical status.

methodsSubjects were 31 PE cases (LPE: n = 17; OPE: n = 14). BA classification was type III (n = 16), type II (n = 1) in LPE and type III (n = 12), type I (n = 1), type II (n = 1) in OPE.

resultsMean ages and weights at PE were similar: 65.5 days, 4.4 kg (LPE) versus 69.3 days, 4.1 kg (OPE); and mean follow-up was 2.5 years for both LPE and OPE. Jaundice clearance (T-bil ≤1.2 mg/dL) was achieved in 16/17 (94.1 %) after LPE versus 10/14 (71.4 %) after OPE (p = NS), but 3BM were closer to normal after OPE. At the time of review, 13/17 LPE cases (76.5 %) were alive with native livers and 4/17 had received LTx (23.5 %) and 10/14 OPE cases (71.4 %) were alive with native livers and 4/14 had received LTx (28.6 %).

conclusionsAlthough JC was better after LPE, 3BM were better after OPE. Further follow-up will prove the comprehensive prognostic value of 3BM.

Indexed as

LaparoscopyPortoenterostomy, HepaticBiliary AtresiaBiomarkersFemaleHumansInfantMalePostoperative ComplicationsPrognosisTreatment OutcomeBiomarkersBiliary atresiaBiochemistryLaparoscopyLiver function

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.