ArticleEuropean journal of epidemiology2015
Childhood cancer and residential exposure to highways: a nationwide cohort study.
Article in European journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026Pooled it
- Association between Outdoor Air Pollution and Childhood Leukemia: A Systematic Review and Dose-Response Meta-Analysis.Environmental health perspectives · 2019Pooled it
- The association between air pollution exposure and childhood cancer: a scoping review about the challenges in epidemiological studies.BMC public health · 2025Article
- Traffic-related air pollution exposure at birth and risk of childhood leukemia: results from the GEOCAP-Birth case-control study.Environmental health : a global access science source · 2025Article
- Clustering of childhood acute leukemia in Finland: a nationwide register-based study.Cancer causes & control : CCC · 2025Article
- Exposures from Oil and Gas Development and Childhood Leukemia Risk in Colorado: A Population-Based Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Examining the relationship between land use and childhood leukemia and lymphoma in Tehran.Scientific reports · 2024Article
- Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade.International journal of molecular sciences · 2024Article
- An Overview of How the Built Environment Relates to Children's Health.Current environmental health reports · 2023Review
- Multi-Hazard property buyouts: Making a case for the acquisition of flood and contaminant-prone residential properties in Galena Park, TX.Climate risk management · 2023Article
- Clinical data for paediatric research: the Swiss approach : Proceedings of the National Symposium in Bern, Switzerland, Dec 5-6, 2019.BMC proceedings · 2021Article
- Birth characteristics and childhood leukemia in Switzerland: a register-based case-control study.Cancer causes & control : CCC · 2021Article
- Identification of high-risk and low-risk clusters and estimation of the relative risk of acute lymphoblastic leukemia in provinces of Iran during 2006-2014 period: A geo-epidemiological study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Residential Exposure to PMInternational journal of environmental research and public health · 2020Article
- Air pollution exposure at the residence and risk of childhood cancers in Denmark: A nationwide register-based case-control study.EClinicalMedicine · 2020Article
- Outdoor air pollution and cancer: An overview of the current evidence and public health recommendations.CA: a cancer journal for clinicians · 2020Review
- Bayesian spatial modelling of childhood cancer incidence in Switzerland using exact point data: a nationwide study during 1985-2015.International journal of health geographics · 2020Article
- Registries and collaborative studies for primary ciliary dyskinesia in Europe.ERJ open research · 2020Review
- Maternal Residential Proximity to Major Roadways and the Risk of Childhood Acute Leukemia: A Population-Based Case-Control Study in Texas, 1995-2011.International journal of environmental research and public health · 2019Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Children living near highways are exposed to higher concentrations of traffic-related carcinogenic pollutants. Several studies reported an increased risk of childhood cancer associated with traffic exposure, but the published evidence is inconclusive. We investigated whether cancer risk is associated with proximity of residence to highways in a nation-wide cohort study including all children aged <16 years from Swiss national censuses in 1990 and 2000. Cancer incidence was investigated in time to event analyses (1990-2008) using Cox proportional hazards models and incidence density analyses (1985-2008) using Poisson regression. Adjustments were made for socio-economic factors, ionising background radiation and electromagnetic fields. In time to event analysis based on 532 cases the adjusted hazard ratio for leukaemia comparing children living <100 m from a highway with unexposed children (≥500 m) was 1.43 (95 % CI 0.79, 2.61). Results were similar in incidence density analysis including 1367 leukaemia cases (incidence rate ratio (IRR) 1.57; 95 % CI 1.09, 2.25). Associations were similar for acute lymphoblastic leukaemia (IRR 1.64; 95 % CI 1.10, 2.43) and stronger for leukaemia in children aged <5 years (IRR 1.92; 95 % CI 1.22, 3.04). Little evidence of association was found for other tumours. Our study suggests that young children living close to highways are at increased risk of developing leukaemia.
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