ArticlePreventive veterinary medicine2015
A new compartmental model of Mycobacterium avium subsp. paratuberculosis infection dynamics in cattle.
Article in Preventive veterinary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Use of ELISA to predict highJournal of veterinary research · 2026Article
- Weighted gene co-expression network analysis reveals key genes and lncRNAs inFrontiers in immunology · 2026Article
- Dual effects of probiotic administration prior to Mycobacterium avium subsp. paratuberculosis infection are associated with immunological and microbiota shifts.Scientific reports · 2025Article
- Successful Control ofAnimals : an open access journal from MDPI · 2024Article
- Presence of antibodies against Mycobacterium avium subspecies paratuberculosis in Brazilian high-producing dairy herds.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Modeling Paratuberculosis Transmission in a Small Dairy Herd Typical of Slovenia Suggests That Different Models Should Be Used to Study Disease Spread in Herds of Different Sizes.Animals : an open access journal from MDPI · 2022Article
- Investigating effective testing strategies for the control of Johne's disease in western Canadian cow-calf herds using an agent-based simulation model.Frontiers in veterinary science · 2022Article
- Modelling spread and surveillance of Mycobacterium avium subsp. paratuberculosis in the Swedish cattle trade network.Preventive veterinary medicine · 2020Article
- Characterizing infectious disease progression through discrete states using hidden Markov models.PloS one · 2020Article
- Mastitis risk effect on the economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study.PloS one · 2019Article
- Implications of Cattle Trade for the Spread and Control of Infectious Diseases in Slovenia.Frontiers in veterinary science · 2019Article
- Control measures to prevent the increase of paratuberculosis prevalence in dairy cattle herds: an individual-based modelling approach.Veterinary research · 2018Article
- Evaluating the impact of transmission mode, calibration level and farmer compliance in simulation models of paratuberculosis in dairy herds.Scientific reports · 2018Article
- A data-driven individual-based model of infectious disease in livestock operation: A validation study for paratuberculosis.PloS one · 2018Article
- Which phenotypic traits of resistance should be improved in cattle to control paratuberculosis dynamics in a dairy herd: a modelling approach.Veterinary research · 2017Article
- Use of an Individual-based Model to Control Transmission Pathways of Mycobacterium avium Subsp. paratuberculosis Infection in Cattle Herds.Scientific reports · 2017Article
- Economic consequences of paratuberculosis control in dairy cattle: A stochastic modeling study.Preventive veterinary medicine · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Models of Mycobacterium avium subsp. paratuberculosis (MAP), a chronic infectious agent of cattle, are used to identify effective control programs. However, new biological findings show that adult infections occur and that infected animals can be separated into 2 paths: animals that will become high-shedding and, eventually, experience clinical disease (high-path); and animals that will shed only small quantities of MAP and will remain subclinical (low-path). Longitudinal data analysis found that high-path animals progress more quickly than previously believed. A standard model of MAP transmission in dairy herds was modified to include adult low-path infections and 2 infection pathways for infected calves. Analysis of this model showed that adult infection may play an important role in MAP dynamics on a dairy farm, and that the increased rate of progression for high-path animals influences both the prevalence and the persistence of MAP on a dairy farm. This new model will be able to determine the effectiveness of MAP control programs more accurately than previous models.
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