Evidence map›Paper›PMID 26520159›Full record

ArticleMaternal and child health journal2016

Hepatitis C Seroprevalence Among HIV-Infected Childbearing Women in New York State in 2006.

L Ghazaryan, L Smith, M Parker, C Flanigan, W Pulver, T Sullivan, A Carrascal

Abstract read
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In one paragraph

Article in Maternal and child health journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

L GhazaryanSurveillance and Special Projects Unit, Bureau of STD Prevention and Epidemiology, AIDS Institute, New York State Department of Health, ESP, Corning Tower, Albany, NY, 12237, USA. lusine.ghazaryan@health.ny.gov.
L SmithDivision of Epidemiology, Evaluation and Research, New York State Department of Health, Corning Tower, ESP, Albany, NY, 12237, USA. lou.smith@health.ny.gov.
M ParkerBloodborne Viruses Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY, 12208, USA. monica.parker@health.ny.gov.
C FlaniganViral Hepatitis Section, AIDS Institute, New York State Department of Health, ESP, Corning Tower Room 429, Albany, NY, 12237, USA. colleen.flanigan@health.ny.gov.
W PulverDivision of Epidemiology, Evaluation and Research, New York State Department of Health, Corning Tower, ESP, Albany, NY, 12237, USA. wendy.pulver@health.ny.gov.
T SullivanWadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY, 12208, USA. timothy.sullivan@health.ny.gov.
A CarrascalCancer Control, American Cancer Society, Eastern Division, One Penny Lane, Latham, NY, 12110, USA. alvaro.carrascal@cancer.org.
New York State Department of Health · USAmerican Cancer Society · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify factors associated with maternal hepatitis C virus (HCV) seroprevalence and transmission of HCV as identified by qualitative HCV ribonucleic acid (RNA) in the infants of human immunodeficiency virus (HIV) infected women delivering in New York State (NYS) in 2006. STUDY

designIn this retrospective cohort study of HIV-exposed infants born in NYS, leftover infant plasma from HIV diagnostic testing was de-identified and tested for HCV. If HCV antibodies were detected, a second specimen collected when the infant was >2 months old was tested for HCV qualitative RNA. Multivariate logistic regression was used to identify factors associated with HCV seropositivity.

resultsIn a final sample of 553 live birth events with perinatal HIV exposure, 21 (3.8 %) of tested infant specimens had HCV antibodies indicative of maternal HCV seropositivity. Maternal age at delivery of >35 years, Hispanic ethnicity, white race and injection drug use (IDU) were significantly associated with HCV seropositivity in multivariate analysis. No cases of HCV vertical transmission were identified among HCV exposed infant specimens.

conclusionsThis statewide population-based study of HIV-infected childbearing women shows HCV seroprevalence of 3.8 %. Maternal age of >35 years and IDU are the strongest predictors of HCV seropositivity. Although no viral transmission was documented, more comprehensive longitudinal testing would be required to conclude that HCV transmission did not occur.

Indexed as

AdultEnzyme-Linked Immunosorbent AssayFemaleHepacivirusHepatitis CHepatitis C AntibodiesHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalMaternal AgeMultivariate AnalysisNew YorkPopulation SurveillancePregnancyPregnancy Complications, InfectiousHepatitis C AntibodiesHepatitis CHIVNew York StatePregnantSeroprevalence

Identifiers

PMID26520159
OpenAlexW1926964754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.