Evidence map›Paper›PMID 26520142›Full record

ReviewCurrent diabetes reports2015

Challenges and Opportunities in the Management of Cardiovascular Risk Factors in Youth With Type 1 Diabetes: Lifestyle and Beyond.

Michelle Katz, Elisa Giani, Lori Laffel

Registry-linked trialAbstract readReview
In one paragraph

Review in Current diabetes reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05107544 (Metabolic, Physical Fitness and Mental Health Effects of High Intensity Interval Training), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05107544 nacompletednot on this mapstarted 2021, after this paper: background citation

Metabolic, Physical Fitness and Mental Health Effects of High Intensity Interval Training (HIIT) in Adolescents With Type 1 Diabetes

TypeinterventionalSponsorHospital Las HiguerasRan2021 to 2022Enrolled30ConditionsDiabetes Mellitus, Type 1ArmsHIGH INTENSITY INTERVAL TRAINING
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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  16. Role of growth hormone-releasing hormone in dyslipidemia associated with experimental type 1 diabetes.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michelle KatzGenetics and Epidemiology Section, Harvard Medical School, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA. Michelle.Katz@joslin.harvard.edu.
Elisa GianiGenetics and Epidemiology Section, Harvard Medical School, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA. Elisa.Giani@joslin.harvard.edu.
Lori LaffelGenetics and Epidemiology Section, Harvard Medical School, Joslin Diabetes Center, One Joslin Place, Boston, MA, 02215, USA. lori.laffel@joslin.harvard.edu.
Joslin Diabetes Center · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI AMY JO WAGERS · 1986 to 2026
$50.5M
CAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTSK12DK094721 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LAFFEL, LORI M, WHITE, MORRIS F. · 2011 to 2021
$6.3M
Improving Management Strategies for Blood Pressure and Lipids in Pediatric T1DK23HL125976 · NHLBI · JOSLIN DIABETES CENTER · PI KATZ, MICHELLE LYNNE · 2015 to 2017
$514k
NHLBI NIH HHS K23 HL125976NIDDK NIH HHS K12 DK094721NIDDK NIH HHS P30 DK036836
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in persons with type 1 diabetes (T1D). Specific risk factors associated with diabetes, such as hyperglycemia and kidney disease, have been demonstrated to increase the incidence and progression of CVD. Nevertheless, few data exist on the effects of traditional risk factors such as dyslipidemia, obesity, and hypertension on CVD risk in youth with T1D. Improvements in understanding and approaches to the evaluation and management of CVD risk factors, specifically for young persons with T1D, are desirable. Recent advances in noninvasive techniques to detect early vascular damage, such as the evaluation of endothelial dysfunction and aortic or carotid intima-media thickness, provide new tools to evaluate the progression of CVD in childhood. In the present review, current CVD risk factor management, challenges, and potential therapeutic interventions in youth with T1D are described.

Indexed as

Life StyleAdolescentCardiovascular DiseasesChildDiabetes Mellitus, Type 1HumansHyperglycemiaHypertensionObesityRisk FactorsCardiovascularDiabetes type 1LifestylePediatrics

Identifiers

PMID26520142
PMCPMC4893313
OpenAlexW1947105675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.