ArticleBiology open2015
Context-specific comparison of sleep acquisition systems in Drosophila.
Article in Biology open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
41 citing papers in PubMed.
- Cell-specific variant-to-gene mapping identifies conserved neural and glial regulators of sleep.bioRxiv : the preprint server for biology · 2026Article
- Article
- Targeted single cell expression profiling identifies integrators of sleep and metabolic state.G3 (Bethesda, Md.) · 2025Article
- Activity Monitoring for Analysis of Sleep inCold Spring Harbor protocols · 2024Article
- CRY1 is involved in the take-off behaviour of migratory Cnaphalocrocis medinalis individuals.BMC biology · 2024Article
- Altered circadian rhythm, sleep, andProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Sex- and strain-dependent effects of ageing on sleep and activity patterns in Drosophila.PloS one · 2024Article
- Neurofibromin 1 mediates sleep depth in Drosophila.PLoS genetics · 2023Article
- Modulation and neural correlates of postmating sleep plasticity in Drosophila females.Current biology : CB · 2023Article
- Many faces of sleep regulation: beyond the time of day and prior wake time.The FEBS journal · 2023Review
- Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep.Science advances · 2023Article
- Mating disrupts morning anticipation in Drosophila melanogaster females.PLoS genetics · 2022Article
- Mutation of the Drosophila melanogaster serotonin transporter dSERT impacts sleep, courtship, and feeding behaviors.PLoS genetics · 2022Article
- Mosquito cryptochromes expressed in Drosophila confer species-specific behavioral light responses.Current biology : CB · 2022Article
- Expression of a constitutively active insulin receptor in Drosulfakinin (Dsk) neurons regulates metabolism and sleep inBiochemistry and biophysics reports · 2022Article
- Biological functions of α2-adrenergic-like octopamine receptor in Drosophila melanogaster.Genes, brain, and behavior · 2022Article
- Sleep correlates with behavioral decision making critical for reproductive output in Drosophila melanogaster.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2022Article
- Excessive energy expenditure due to acute physical restraint disrupts Drosophila motivational feeding response.Scientific reports · 2021Article
- Manipulations of the olfactory circuit highlight the role of sensory stimulation in regulating sleep amount.Sleep · 2021Article
- Sleep contributes to preference for novel food odours in Drosophila melanogaster.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Sleep is conserved across phyla and can be measured through electrophysiological or behavioral characteristics. The fruit fly, Drosophila melanogaster, provides an excellent model for investigating the genetic and neural mechanisms that regulate sleep. Multiple systems exist for measuring fly activity, including video analysis and single-beam (SB) or multi-beam (MB) infrared (IR)-based monitoring. In this study, we compare multiple sleep parameters of individual flies using a custom-built video-based acquisition system, and commercially available SB- or MB-IR acquisition systems. We report that all three monitoring systems appear sufficiently sensitive to detect changes in sleep duration associated with diet, age, and mating status. Our data also demonstrate that MB-IR detection appeared more sensitive than the SB-IR for detecting baseline nuances in sleep architecture, while architectural changes associated with varying life-history and environment were generally detected across all acquisition types. Finally, video recording of flies in an arena allowed us to measure the effect of ambient environment on sleep. These experiments demonstrate a robust effect of arena shape and size as well as light levels on sleep duration and architecture, and highlighting the versatility of tracking-based sleep acquisition. These findings provide insight into the context-specific basis for choosing between Drosophila sleep acquisition systems, describe a novel cost-effective system for video tracking, and characterize sleep analysis using the MB-IR sleep analysis. Further, we describe a modified dark-place preference sleep assay using video tracking, confirming that flies prefer to sleep in dark locations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.