ArticleApplied and environmental microbiology2016
Mechanisms of Inactivation by High-Voltage Atmospheric Cold Plasma Differ for Escherichia coli and Staphylococcus aureus.
Article in Applied and environmental microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 413 citations in OpenAlex.
- Piezoelectric cold atmospheric plasma inactivates dairy cattle bacteria and potentiates antibiotics in vitro.Applied microbiology and biotechnology · 2026Article
- Water microdroplet platforms for sustainable, reagent-free viral disinfection.Journal of biological engineering · 2026Article
- The power of neutralization: the critical step for the accurate antimicrobial potential of plasma-activated water.Frontiers in microbiology · 2026Article
- Cold atmospheric plasma mediates antibiofilm activity and sensitization to further plasma and antibiotic challenges againstFEMS microbes · 2026Article
- Submerged Spark Plasma Discharges for the Removal of Antibiotics, Antibiotic-Resistant Bacteria, and Resistance Genes.Plasma chemistry and plasma processing · 2026Article
- Inactivation of Listeria monocytogenes and Salmonella Typhimurium by piezoelectric cold plasma: oxidative, structural and metabolic pathways.Archives of microbiology · 2025Article
- Cold Plasma as a Revolutionary Antimicrobial Modality: A Multifaceted Weapon Against Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Impact of Chitooligosaccharide Conjugated Epigallocatechin Gallate and Non-Thermal High-Voltage Atmospheric Cold Plasma onFoods (Basel, Switzerland) · 2025Article
- Biomedical application of cold plasma: navigating through plasma types and devices by antimicrobial effectiveness and tissue tolerance.Advanced therapeutics · 2025Article
- Utilizing onion peel extract as photosensitizer combined with 405 nm blue light to control Salmonella Typhimurium on eggshells.Journal of food science · 2025Article
- Evaluation of cold atmospheric pressure plasma effects onIranian journal of microbiology · 2025Article
- Plasma Optimization as a Novel Tool to Explore Plant-Microbe Interactions in Climate Smart Agriculture.Microorganisms · 2025Review
- Reactive molecular dynamics simulations investigating ROS-mediated HIV damage from outer gp120 protein to internal capsid protein.RSC advances · 2025Article
- Cold Plasma Treatment forJournal of lasers in medical sciences · 2025Review
- Cold Plasma-A Sustainable Energy-Efficient Low-Carbon Food Processing Technology: Physicochemical Characteristics, Microbial Inactivation, and Industrial Applications.International journal of food science · 2025Review
- Inactivation of multidrug-resistant bacteria using cold atmospheric-pressure plasma technology.Frontiers in medicine · 2025Article
- Combating foodborne pathogens: Efficacy of plasma-activated water with supplementary methods forFood chemistry: X · 2024Article
- Sublethal Damage Caused by Cold Plasma onFoods (Basel, Switzerland) · 2024Article
- Guided Plasma Application in Dentistry-An Alternative to Antibiotic Therapy.Antibiotics (Basel, Switzerland) · 2024Article
- Non-thermal obliteration of critically ranked carbapenem-resistant Acinetobacter baumannii and its resistance gene in a batch atmospheric plasma reactor.Environmental science and pollution research international · 2024Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atmospheric cold plasma (ACP) is a promising nonthermal technology effective against a wide range of pathogenic microorganisms. Reactive oxygen species (ROS) play a crucial inactivation role when air or other oxygen-containing gases are used. With strong oxidative stress, cells can be damaged by lipid peroxidation, enzyme inactivation, and DNA cleavage. Identification of ROS and an understanding of their role are important for advancing ACP applications for a range of complex microbiological issues. In this study, the inactivation efficacy of in-package high-voltage (80 kV [root mean square]) ACP (HVACP) and the role of intracellular ROS were investigated. Two mechanisms of inactivation were observed in which reactive species were found to either react primarily with the cell envelope or damage intracellular components. Escherichia coli was inactivated mainly by cell leakage and low-level DNA damage. Conversely, Staphylococcus aureus was mainly inactivated by intracellular damage, with significantly higher levels of intracellular ROS observed and little envelope damage. However, for both bacteria studied, increasing treatment time had a positive effect on the intracellular ROS levels generated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.