Evidence map›Paper›PMID 26519062›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2016

Transcriptional Profiling of Candida albicans in the Host.

Kearney T W Gunsalus, Carol A Kumamoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Anti-Infection of Oral Microorganisms from Herbal Medicine ofDrug design, development and therapy · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kearney T W GunsalusDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA, 02111, USA.
Carol A KumamotoDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA, 02111, USA. carol.kumamoto@tufts.edu.

Funding

Training in Education and Critical Research SkillsK12GM074869 · NIGMS · TUFTS UNIVERSITY BOSTON · PI MOORE, CLAIRE L · 2006 to 2017
$8.5M
Contact sensing and C. albicans-host interactionR01AI081794 · NIAID · TUFTS UNIVERSITY BOSTON · PI KUMAMOTO, CAROL A. · 2010 to 2014
$2.2M
NIAID NIH HHS R01 AI081794NIAID NIH HHS R01AI081794NIGMS NIH HHS K12 GM074869NIGMS NIH HHS K12GM074869
6 · The paper itself

Abstract

Gene expression profiling has become an important tool for determining gene functions, performing phenotypic analysis, and quantifying the differential expression of individual transcripts under various conditions. Candida albicans gene expression is highly responsive to environmental conditions and rapidly adapts to various niches within the host. Here, we describe a mouse model of gastrointestinal colonization with C. albicans, the measurement of colonization in fecal pellets, and the collection of samples for transcriptional profiling. We describe how to extract and purify RNA suitable for analysis via RT-qPCR or microarray.

Indexed as

Gene Expression ProfilingGene Expression Regulation, FungalHost-Pathogen InteractionsAnimalsCandida albicansCandidiasisFemaleMiceReverse Transcriptase Polymerase Chain ReactionCandida albicansGene expressionHostRNATranscriptional profiling

Identifiers

PMID26519062
PMCPMC4750373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.