Evidence map›Paper›PMID 26518723›Full record

ReviewJournal of controlled release : official journal of the Controlled Release Society2016

Nanoparticles and nanofibers for topical drug delivery.

Ritu Goyal, Lauren K Macri, Hilton M Kaplan, Joachim Kohn

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of controlled release : official journal of the Controlled Release Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed.

  1. Trial
  2. Review
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  4. Article
  5. Multi-hierarchical biofunctional polymeric biomaterial to promote wound closure.Journal of materials science. Materials in medicine · 2026
    Article
  6. Review
  7. Review
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  11. Review
  12. Review
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  15. Article
  16. Article
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  18. Article
  19. Article
  20. Review

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ritu GoyalNew Jersey Center for Biomaterials, Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Lauren K MacriNew Jersey Center for Biomaterials, Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Hilton M KaplanNew Jersey Center for Biomaterials, Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Joachim KohnNew Jersey Center for Biomaterials, Rutgers, The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA. Electronic address: kohn@dls.rutgers.edu.

Funding

Translational Research in Regenerative MedicineT32EB005583 · NIBIB · RUTGERS, THE STATE UNIV OF N.J. · PI LEE, KIBUM, PAREKKADAN, BIJU · 2006 to 2022
$4.7M
An engineered graft to encourage preferential motor reinnervation following peripR01NS078385 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI KOHN, JOACHIM B., SCHACHNER, MELITTA · 2012 to 2016
$2.9M
NIBIB NIH HHS T32 EB005583NINDS NIH HHS R01 NS078385
6 · The paper itself

Abstract

This review provides the first comprehensive overview of the use of both nanoparticles and nanofibers for topical drug delivery. Researchers have explored the use of nanotechnology, specifically nanoparticles and nanofibers, as drug delivery systems for topical and transdermal applications. This approach employs increased drug concentration in the carrier, in order to increase drug flux into and through the skin. Both nanoparticles and nanofibers can be used to deliver hydrophobic and hydrophilic drugs and are capable of controlled release for a prolonged period of time. The examples presented provide significant evidence that this area of research has - and will continue to have - a profound impact on both clinical outcomes and the development of new products.

Indexed as

Administration, CutaneousAnimalsDrug Delivery SystemsHumansNanofibersNanoparticlesSkin AbsorptionDrug deliveryElectrospun fiber matsNanofibersNanoparticlesSkinTopical

Identifiers

PMID26518723
PMCPMC4896846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.