ArticleInsights into imaging2016
Orbital tumours and tumour-like lesions: exploring the armamentarium of multiparametric imaging.
Article in Insights into imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Methods of diffusion MRI tractography for localization of the anterior optic pathway: A systematic review of validated methods.NeuroImage. Clinical · 2023Pooled it
- An Incidental EWSR1-Rearranged Sarcoma of the Orbit with Primitive Neuroectodermal Morphology and Myogenic Differentiation: A Case Report and Diagnostic Challenge".Asian journal of neurosurgery · 2026Article
- Value of high-frequency color Doppler ultrasound for preorbital mass diagnosis.Indian journal of ophthalmology · 2026Article
- The evolving role of interventional radiology in ophthalmology: advancements in imaging, therapeutic applications, and future prospects, a narrative review.Annals of medicine and surgery (2012) · 2026Article
- Article
- Pediatric orbital masses from a tertiary pediatric oncology referral center: clinical characteristics and survival outcomes from a 20-year single-center experience.BMC pediatrics · 2026Article
- Extranodal MALT lymphoma masquerading as a cavernous hemangioma: A diagnostic and surgical challenge.Radiology case reports · 2026Article
- Comparative Clinical Outcomes of Different Orbitotomy Approaches in the Surgical Management of Orbital Tumors.Journal of ophthalmology · 2026Article
- Application of imaging studies for orbital tumors: a practical review and representative cases.Frontiers in ophthalmology · 2026Review
- Transorbital Neuroendoscopic Surgery: A Comprehensive Review for Managing Intracranial Lesions with Orbital Access.Neuro-ophthalmology (Aeolus Press) · 2025Review
- Anatomy of the medial wall of the orbit undergoing an endoscopic endonasal approach: An inferomedial and superomedial approach.Surgical neurology international · 2025Article
- The application of ultrasonography in the differential diagnosis of orbital lesions.Frontiers in ophthalmology · 2025Review
- Biphenotypic Sinonasal Sarcoma with Orbital Invasion: A Literature Review and Modular System of Surgical Approaches.Cancers · 2024Review
- Pediatric orbital lesions: non-neoplastic extraocular soft-tissue lesions.Pediatric radiology · 2024Article
- Case report: Orbital myeloid sarcoma: a report of two rare cases and review of the literature.Pathology oncology research : POR · 2024Review
- Clinical characteristics, diagnosis, and outcomes of orbital biopsies in a single Irish centre.Irish journal of medical science · 2023Article
- Brain Tumors Affecting the Orbit Globe and Orbit Tumors Affecting the Brain.Advances in experimental medicine and biology · 2023Article
- Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature.Mediterranean journal of hematology and infectious diseases · 2023Article
- Accuracy between clinical and radiological diagnoses compared to surgical orbital biopsies.International journal of ophthalmology · 2023Article
- Orbital Tumors-Clinical, Radiologic and Histopathologic Correlation.Diagnostics (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the orbit is a small anatomical space, the wide range of structures present within it are often the site of origin of various tumours and tumour-like conditions, both in adults and children. Cross-sectional imaging is mandatory for the detection, characterization, and mapping of these lesions. This review focuses on multiparametric imaging of orbital tumours. Each tumour is reviewed in relation to its clinical presentation, compartmental location, imaging characteristics, and its histological features. We herein describe orbital tumours as lesions of the globe (retinoblastoma, uveal melanoma), optic nerve sheath complex (meningioma, optic nerve glioma), conal-intraconal compartment (hemangioma), extraconal compartment (dermoid/epidermoid, lacrimal gland tumours, lymphoma, rhabdomysarcoma), and bone and sinus compartment (fibrous dysplasia). Lesions without any typical compartmental localization and those with multi-compartment involvement (veno-lymphatic malformation, plexiform neurofibroma, idiopathic orbital pseudotumour, IgG4 related disease, metastases) are also reviewed. We discuss the role of advanced imaging techniques, such as MR diffusion-weighted imaging (DWI), diffusion tensor imaging, fluoro-2-deoxy-D-glucose positron emission tomography CT (FDG-PET CT), and positron emission tomography MRI (MRI PET) as problem-solving tools in the evaluation of those orbital masses that present with non-specific morphologic imaging findings. Main messages/Teaching points • A compartment-based approach is essential for the diagnosis of orbital tumours. • CT and MRI play a key role in the work-up of orbital tumours. • DWI, PET CT, and MRI PET are complementary tools to solve diagnostic dilemmas. • Awareness of salient imaging pearls and diagnostic pitfalls avoids interpretation errors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.