Evidence map›Paper›PMID 26518591›Full record

ArticleJournal of the International Association of Providers of AIDS Care2016

Cholesterol Levels in HIV- and/or HCV-Infected Drug Users Living in Argentina.

Rakhi Kohli, Diana Winston, Heidi Sheehan, Estela Muzzio, Jorge Benetucci, Mercedes Weissenbacher, Christine Wanke, Tamsin Knox, Alice Tang

Open access · goldAbstract read
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rakhi KohliDivision of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA, USA rkohli@tuftsmedicalcenter.org.
Diana WinstonDivision of Gastroenterology, Tufts Medical Center, Boston, MA, USA.
Heidi SheehanDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Estela MuzzioCentro Nacional de Reeducación Social, Buenos Aires, Argentina.
Jorge BenetucciFundación de Ayuda al Inmunodeficiente, Buenos Aires, Argentina.
Mercedes WeissenbacherAcademia Nacional de Medicina, Buenos Aires, Argentina.
Christine WankeDivision of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, MA, USA Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Tamsin KnoxDivision of Gastroenterology, Tufts Medical Center, Boston, MA, USA Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Alice TangDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Tufts Medical Center · USTufts University · USAcademia Nacional de Medicina · AR

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Nutrition and Metabolism CoreP30DA013868 · NIDA · TUFTS UNIVERSITY BOSTON · PI WANKE, CHRISTINE A · 2002 to 2012
$10.0M
NIAID NIH HHS P30 AI042853NIDA NIH HHS P30 DA013868
6 · The paper itself

Abstract

Improved understanding of cholesterol levels in HIV- and hepatitis C virus (HCV)-infected persons in Argentina will guide optimal antiretroviral therapy. The authors conducted a cross-sectional study in Argentina to describe associations between HIV, HCV, and cholesterol. Of the 202 participants, 21 were HIV infected, 15 were HCV infected, 46 were HIV/HCV coinfected, and 120 were HIV/HCV uninfected. HIV/HCV-uninfected participants had the highest total cholesterol (TC) and low-density lipoprotein (LDL) levels. Multivariate modeling revealed that HIV/HCV-coinfected patients had the lowest TC levels (-28.7 mg/dL, P < .001) compared to the HIV/HCV-uninfected reference group. Hepatitis C virus and HIV/HCV coinfection were associated with lower LDL levels (-21.4 mg/dL, P = .001 and -20.3 mg/dL, P < .0001, respectively). HIV and HIV/HCV coinfection, but not HCV alone, were associated with lower high-density lipoprotein levels (-9.1 mg/dL, P = .0008 and -6.8 mg/dL, P = .0006, respectively). Further study is needed to examine whether the more favorable lipid profile observed in HIV/HCV-coinfected persons is associated with a reduction in cardiovascular risk.

Indexed as

CoinfectionHepatitis CHIV InfectionsAdultArgentinaCholesterolCross-Sectional StudiesFemaleHumansMaleYoung AdultCholesterolArgentinacholesterolhepatitis CHIV

Identifiers

PMID26518591
PMCPMC4851908
OpenAlexW1845811228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.