Evidence map›Paper›PMID 26518253›Full record

ArticleDrug and alcohol dependence2015

Characterizing pain and associated coping strategies in methadone and buprenorphine-maintained patients.

Kelly E Dunn, Patrick H Finan, D Andrew Tompkins, Michael Fingerhood, Eric C Strain

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kelly E DunnDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: kdunn9@jhmi.edu.
Patrick H FinanDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
D Andrew TompkinsDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Michael FingerhoodDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Eric C StrainDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in HumansR01DA035246 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2014 to 2018
$3.2M
Mentoring of Clinical Investigators in Patient Oriented ResearchK24DA023186 · NIDA · JOHNS HOPKINS UNIVERSITY · PI STRAIN, ERIC C. · 2007 to 2016
$1.8M
Optimizing Pain Treatment while Reducing Abuse Liability in Opioid DependenceK23DA029609 · NIDA · JOHNS HOPKINS UNIVERSITY · PI TOMPKINS, DAVID ANDREW · 2012 to 2016
$929k
Sleep disturbance as a putative mechanism for reward system dysfunctionK23DA035915 · NIDA · JOHNS HOPKINS UNIVERSITY · PI FINAN, PATRICK · 2014 to 2018
$838k
Development and Validation of a Computerized Opioid Overdose InterventionR21DA035327 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2013 to 2014
$446k
NIDA NIH HHS K23 DA029609NIDA NIH HHS K23DA029609NIDA NIH HHS K23 DA035915NIDA NIH HHS K23DA035915NIDA NIH HHS K24 DA023186NIDA NIH HHS K24DA023186NIDA NIH HHS R01 DA035246NIDA NIH HHS R01DA035246NIDA NIH HHS R21 DA035327NIDA NIH HHS R21DA035327
6 · The paper itself

Abstract

backgroundChronic pain is common among patients receiving opioid maintenance treatment (OMT) for opioid use disorder. To aid development of treatment recommendations for coexisting pain and opioid use disorder, it is necessary to characterize pain treatment needs and assess whether needs differ as a function of OMT medication.

methodsA point-prevalence survey assessing pain and engagement in coping strategies was administered to 179 methadone and buprenorphine-maintained patients.

resultsForty-two percent of participants were categorized as having chronic pain. Methadone patients had greater severity of pain relative to buprenorphine patients, though both groups reported high levels of interference with daily activities, and participants with pain attended the emergency room more frequently relative to participants without pain. Only 2 coping strategies were being utilized by more than 50% of participants (over-the-counter medication, prayer).

conclusionsResults indicate that pain among OMT patients is common, severe, and of significant impairment. Methadone patients reported greater severity pain, particularly worse pain in the past 24h, though interference from pain in daily activities did not vary as a function of OMT. Most participants with pain were utilizing few evidenced-based pain coping strategies. Increasing OMT patient access to additional pain treatment strategies is an opportunity for immediate intervention, and similarities across OMT type suggest interventions do not need to be customized to methadone vs. buprenorphine patients.

Indexed as

Adaptation, PsychologicalAdultAnalgesics, OpioidBuprenorphineChronic PainFemaleHumansMaintenance ChemotherapyMaleMethadoneMiddle AgedOpioid-Related DisordersPain ManagementPain ThresholdPrevalenceAnalgesics, OpioidBuprenorphineMethadoneBuprenorphineChronic painCopingMethadoneOpioid

Identifiers

PMID26518253
PMCPMC4663104
OpenAlexW2109838101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.