ArticleVeterinary research2015
Patterns of Mycobacterium tuberculosis-complex excretion and characterization of super-shedders in naturally-infected wild boar and red deer.
Article in Veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 81 citations in OpenAlex.
- Shedding-weighted network approaches for understanding tuberculosis maintenance in multihost systems using camera traps.Ecological applications : a publication of the Ecological Society of America · 2026Article
- Climate and mammal host community characteristics drive tuberculosis maintenance at the wildlife livestock interface.One health (Amsterdam, Netherlands) · 2026Article
- Effect of Lactic Acid Bacteria-Derived Postbiotic Supplementation on Tuberculosis in Wild Boar Populations.Pathogens (Basel, Switzerland) · 2024Article
- Heavy metal and metalloid concentrations in red deer (Cervus elaphus) and their human health implications from One Health perspective.Environmental geochemistry and health · 2024Article
- Tuberculosis in Wild Pigs from Argentina.EcoHealth · 2024Article
- Antemortem detection of Mycobacterium bovis in nasal swabs from African rhinoceros.Scientific reports · 2024Article
- Detection of non-tuberculous mycobacteria in native wildlife species at conservation risk of Argentina.Frontiers in veterinary science · 2024Article
- Genomic epidemiology sheds light on the emergence and spread ofEmerging microbes & infections · 2023Article
- Will we ever eradicate animal tuberculosis?Irish veterinary journal · 2023Article
- Using integrated wildlife monitoring to prevent future pandemics through one health approach.One health (Amsterdam, Netherlands) · 2023Article
- A study of the incidence of bovine tuberculosis in the wild red deer herd of Exmoor.European journal of wildlife research · 2023Article
- Epidemiology ofProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Detection of Mycobacterium tuberculosis complex DNA in oronasal swabs from infected African buffaloes (Syncerus caffer).Scientific reports · 2022Article
- Article
- The source and fate of Mycobacterium tuberculosis complex in wastewater and possible routes of transmission.BMC public health · 2022Article
- Occupational exposure and challenges in tackling M. bovis at human-animal interface: a narrative review.International archives of occupational and environmental health · 2021Review
- Characterization of potential superspreader farms for bovine tuberculosis: A review.Veterinary medicine and science · 2021Review
- Long-term molecular surveillance provides clues on a cattle origin for Mycobacterium bovis in Portugal.Scientific reports · 2020Article
- Long-term efficacy of BCG vaccination in goat herds with a high prevalence of tuberculosis.Scientific reports · 2020Article
- Long-Term Determinants of Tuberculosis in the Ungulate Host Community of Doñana National Park.Pathogens (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wild boar (Sus scrofa) and red deer (Cervus elaphus) are the main maintenance hosts for bovine tuberculosis (bTB) in continental Europe. Understanding Mycobacterium tuberculosis complex (MTC) excretion routes is crucial to define strategies to control bTB in free-ranging populations, nevertheless available information is scarce. Aiming at filling this gap, four different MTC excretion routes (oronasal, bronchial-alveolar, fecal and urinary) were investigated by molecular methods in naturally infected hunter-harvested wild boar and red deer. In addition MTC concentrations were estimated by the Most Probable Number method. MTC DNA was amplified in all types of excretion routes. MTC DNA was amplified in at least one excretion route from 83.0% (CI95 70.8-90.8) of wild ungulates with bTB-like lesions. Oronasal or bronchial-alveolar shedding were detected with higher frequency than fecal shedding (p < 0.001). The majority of shedders yielded MTC concentrations <10(3) CFU/g or mL. However, from those ungulates from which oronasal, bronchial-alveolar and fecal samples were available, 28.2% of wild boar (CI95 16.6-43.8) and 35.7% of red deer (CI95 16.3-61.2) yielded MTC concentrations >10(3) CFU/g or mL (referred here as super-shedders). Red deer have a significantly higher risk of being super-shedders compared to wild boar (OR = 11.8, CI95 2.3-60.2). The existence of super-shedders among the naturally infected population of wild boar and red deer is thus reported here for the first time and MTC DNA concentrations greater than the minimum infective doses were estimated in excretion samples from both species.
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