Evidence map›Paper›PMID 26518235›Full record

ArticleBMC pregnancy and childbirth2015

Relationship between body mass index and mean arterial pressure in normotensive and chronic hypertensive pregnant women: a prospective, longitudinal study.

Luís Guedes-Martins, Mariana Carvalho, Catarina Silva, Ana Cunha, Joaquim Saraiva, Filipe Macedo, Henrique Almeida, A Rita Gaio

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Pathophysiology of Maternal Obesity and Hypertension in Pregnancy.Journal of cardiovascular development and disease · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Luís Guedes-MartinsDepartment of Women and Reproductive Medicine, Hospital Centre of Porto EPE, Largo Prof. Abel Salazar, 4099-001, Porto, Portugal. luis.guedes.martins@gmail.com.
Mariana CarvalhoInstitute of Biomedical Sciences Abel Salazar, University of Porto, 4050-313, Porto, Portugal. marianaslcc@hotmail.com.
Catarina SilvaDepartment of Mathematics, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal. catarinajoaosilva16@gmail.com.
Ana CunhaDepartment of Women and Reproductive Medicine, Hospital Centre of Porto EPE, Largo Prof. Abel Salazar, 4099-001, Porto, Portugal. anacpcunha@gmail.com.
Joaquim SaraivaDepartment of Women and Reproductive Medicine, Hospital Centre of Porto EPE, Largo Prof. Abel Salazar, 4099-001, Porto, Portugal. saraivajp@hotmail.com.
Filipe MacedoDepartment of Cardiology, Faculty of Medicine, University of Porto, 4200-319, Porto, Portugal. filipe.macedo@hsjoao.min-saude.pt.
Henrique AlmeidaDepartment of Women and Reproductive Medicine, Hospital Centre of Porto EPE, Largo Prof. Abel Salazar, 4099-001, Porto, Portugal. almeidah@med.up.pt.
A Rita GaioDepartment of Mathematics, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal. argaio@fc.up.pt.
Universidade do Porto · PTCentro Hospitalar do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBeing overweight is associated with both higher systolic blood pressure (SBP) and diastolic blood pressure (DBP) during pregnancy and increased risk of gestational hypertensive disorders. The objective of this study was to determine and quantify the effect of body mass index (BMI) on mean arterial pressure (MAP) at several time points throughout pregnancy in normotensive (NT) and chronic hypertensive pregnant (HT) women.

methodsA prospective longitudinal study was carried out in 461 singleton pregnancies (429 low-risk and 32 with chronic arterial hypertension), with measurements taken at the 1(st), 2(nd), and 3(rd) trimesters and at delivery. Linear mixed-effects regression models were used to evaluate the time-progression of BMI, SBP, DBP and MAP during pregnancy (NT vs. HT). The longitudinal effect of BMI on MAP, adjusted for the hypertensive status, was investigated by the same methodology.

resultsBMI consistently increased with time in both NT and HT women. In contrast, MAP decreased during the first half of pregnancy, after which it increased until the moment of delivery in both groups. A 5-unit increase in BMI was predicted to produce an increase of approximately 1 mmHg in population MAP values. This effect is independent from the time period and from hypertensive status.

conclusionsIn both NT and HT pregnant women, MAP is strongly (and significantly) influenced by increases in BMI.

Indexed as

Body Mass IndexAdolescentAdultArterial PressureFemaleHumansHypertensionHypertension, Pregnancy-InducedLongitudinal StudiesObesityPregnancyPregnancy TrimestersProspective StudiesRisk FactorsWhite PeopleYoung Adult

Identifiers

PMID26518235
PMCPMC4628392
OpenAlexW1875706310

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.