ArticleeLife2015
Mapping nonlinear receptive field structure in primate retina at single cone resolution.
Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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Who cites it
52 citing papers in PubMed, 106 citations in OpenAlex.
- A standard model for the vertebrate retina.Vision research · 2026Article
- An image-computable spatio-chromatic receptive field model of the midget retinal ganglion cell mosaic across the retina.Journal of computational neuroscience · 2026Article
- Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies.PLoS computational biology · 2026Article
- Nonlinear integration of sensory inputs and behavioral state by a single neuron in C. elegans.Current biology : CB · 2025Article
- Novel color via stimulation of individual photoreceptors at population scale.Science advances · 2025Article
- FOUNDATIONS OF VISUAL FORM SELECTIVITY IN MACAQUE AREAS V1 AND V2.bioRxiv : the preprint server for biology · 2025Article
- Article
- Fixational eye movements enhance the precision of visual information transmitted by the primate retina.Nature communications · 2024Article
- Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina.PLoS computational biology · 2024Article
- Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina.bioRxiv : the preprint server for biology · 2024Article
- Optimization-Based Pairwise Interaction Point Process (O-PIPP): A Precise and Universal Retinal Mosaic Modeling Approach.Investigative ophthalmology & visual science · 2024Article
- Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons.Animals : an open access journal from MDPI · 2024Article
- Estimating receptive fields of simple and complex cells in early visual cortex: A convolutional neural network model with parameterized rectification.PLoS computational biology · 2024Article
- Simple model for encoding natural images by retinal ganglion cells with nonlinear spatial integration.PLoS computational biology · 2022Article
- Inhibition, but not excitation, recovers from partial cone loss with greater spatiotemporal integration, synapse density, and frequency.Cell reports · 2022Article
- Impact of Photoreceptor Loss on Retinal Circuitry.Annual review of vision science · 2021Review
- Interphotoreceptor coupling: an evolutionary perspective.Pflugers Archiv : European journal of physiology · 2021Review
- The Relationship Between Visual Sensitivity and Eccentricity, Cone Density and Outer Segment Length in the Human Foveola.Investigative ophthalmology & visual science · 2021Article
- Nonlinear spatial integration in retinal bipolar cells shapes the encoding of artificial and natural stimuli.Neuron · 2021Article
- Nonlinear Spatial Integration Underlies the Diversity of Retinal Ganglion Cell Responses to Natural Images.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 3 countries.
Funding
Abstract
The function of a neural circuit is shaped by the computations performed by its interneurons, which in many cases are not easily accessible to experimental investigation. Here, we elucidate the transformation of visual signals flowing from the input to the output of the primate retina, using a combination of large-scale multi-electrode recordings from an identified ganglion cell type, visual stimulation targeted at individual cone photoreceptors, and a hierarchical computational model. The results reveal nonlinear subunits in the circuity of OFF midget ganglion cells, which subserve high-resolution vision. The model explains light responses to a variety of stimuli more accurately than a linear model, including stimuli targeted to cones within and across subunits. The recovered model components are consistent with known anatomical organization of midget bipolar interneurons. These results reveal the spatial structure of linear and nonlinear encoding, at the resolution of single cells and at the scale of complete circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.