Evidence map›Paper›PMID 26517759›Full record

ReviewNeurodegenerative disease management2015

Mild cognitive impairment: an update in Parkinson's disease and lessons learned from Alzheimer's disease.

Jennifer G Goldman, Neelum T Aggarwal, Cynthia D Schroeder

Open access · greenAbstract readReview
In one paragraph

Review in Neurodegenerative disease management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Pathogenesis of PMEpigenomes · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Evolution of diagnostic criteria and assessments for Parkinson's disease mild cognitive impairment.Movement disorders : official journal of the Movement Disorder Society · 2018
    Review
  16. Article
  17. Parkinson's Disease: Cognitive Impairment.Focus (American Psychiatric Publishing) · 2017
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer G GoldmanRush University Medical Center, Department of Neurological Sciences, Section of Parkinson Disease & Movement Disorders, 1725 W. Harrison Street, Suite 755, Chicago, IL 60612, USA.
Neelum T AggarwalRush University Medical Center, Department of Neurological Sciences & Rush Alzheimer's Disease Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA.
Cynthia D SchroederRush University Medical Center, Department of Neurological Sciences, 1735 W. Harrison Street, Suite 306, Chicago, IL 60612, USA.
Rush University Medical Center · US

Funding

Cellular and Molecular Medial Temporal Lobe Pathology in Elderly PreMCI subjectsR01AG043375 · NIA · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI GINSBERG, STEPHEN D, MUFSON, ELLIOTT JAY · 2013 to 2017
$3.6M
BASIC NEUROSCIENCE TRAINING IN AGE-RELATED DISORDERST32AG000269 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI MUFSON, ELLIOTT JAY · 1999 to 2015
$1.9M
NIA NIH HHS R01 AG043375NIA NIH HHS T32 AG000269NIA NIH HHS T32AG000269-15
6 · The paper itself

Abstract

Cognitive dysfunction is an important focus of research in Parkinson's disease (PD) and Alzheimer's disease (AD). While the concept of amnestic mild cognitive impairment (MCI) as a prodrome to AD has been recognized for many years, the construct of MCI in PD is a relative newcomer with recent development of diagnostic criteria, biomarker research programs and treatment trials. Controversies and challenges, however, regarding PD-MCI's definition, application, heterogeneity and different trajectories have arisen. This review will highlight current research advances and challenges in PD-MCI. Furthermore, lessons from the AD field, which has witnessed an evolution in MCI/AD definitions, relevant advances in biomarker research and development of disease-modifying and targeted therapeutic trials will be discussed.

Indexed as

BiomarkersAlzheimer DiseaseCognitive DysfunctionHumansParkinson DiseaseBiomarkersAlzheimer's diseaseamnesticbiomarkercognitivedementiadiagnostic criteriaexecutive functionmild cognitive impairmentnonamnesticParkinson's disease

Identifiers

PMID26517759
PMCPMC4968199
OpenAlexW2146823977

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.