ArticleMemorias do Instituto Oswaldo Cruz2015
Leishmania (Viannia) naiffi: rare enough to be neglected?
Article in Memorias do Instituto Oswaldo Cruz, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Whole-Genome Sequencing and Comparative Genomic Analysis ofMicroorganisms · 2026Article
- Advances and Challenges Regarding American Tegumentary Leishmaniasis in the Amazon: Scientific, Epidemiological and Public Health Perspectives.Revista da Sociedade Brasileira de Medicina Tropical · 2026Review
- Clinical and parasitological features of Leishmania infection among gold miners in the Oiapoque basin, an international Brazil-French Guiana border.PLoS neglected tropical diseases · 2024Article
- Exploring Host-Specificity: Untangling the Relationship betweenMicroorganisms · 2023Article
- Leishmania (Viannia) naiffi Lainson & Shaw 1989.Parasites & vectors · 2023Review
- Updating the knowledge of sand flies (Diptera, Psychodidae) in Rondônia State, Brazil.Biodiversity data journal · 2022Article
- Diagnosis and identification of Leishmania species in patients with cutaneous leishmaniasis in the state of Roraima, Brazil's Amazon Region.Parasites & vectors · 2021Article
- Evaluation of cytochrome b sequence to identify Leishmania species and variants: the case of Panama.Memorias do Instituto Oswaldo Cruz · 2021Article
- An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae.ZooKeys · 2021Article
- Vertical stratification of sand fly diversity in relation to natural infections of Leishmania sp. and blood-meal sources in Jamari National Forest, Rondônia State, Brazil.Parasites & vectors · 2020Article
- Leishmania naiffi and lainsoni in French Guiana: Clinical features and phylogenetic variability.PLoS neglected tropical diseases · 2020Article
- Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: Species typing and flow of travelers and migrants with leishmaniasis.PLoS neglected tropical diseases · 2019Article
- American cutaneous leishmaniasis in French Guiana: an epidemiological update and study of environmental risk factors.International journal of dermatology · 2019Article
- Article
- Intercalated low doses of antimonials for disseminated cutaneous leishmaniasis caused byJAAD case reports · 2018Article
- Article
- Natural Leishmania (Viannia) infections of phlebotomines (Diptera: Psychodidae) indicate classical and alternative transmission cycles of American cutaneous leishmaniasis in the Guiana Shield, Brazil.Parasite (Paris, France) · 2017Article
Corrections and comments
- Erratum issuedCorrection2015
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmania species. Few reports of Leishmania (Viannia) naiffi infection suggest that its occurrence is uncommon and the reported cases present a benign clinical course and a good response to treatment. This study aimed to strengthen the clinical and epidemiological importance of L. (V.) naiffi in the Amazon Region (Manaus, state of Amazonas) and to report therapeutic failure in patients infected with this species. Thirty Leishmania spp samples isolated from cutaneous lesions were characterised by multilocus enzyme electrophoresis. As expected, the most common species was Leishmania (V.) guyanensis (20 cases). However, a relevant number of L. (V.) naiffi patients (8 cases) was observed, thus demonstrating that this species is not uncommon in the region. No patient infected with L. (V.) naiffi evolved to spontaneous cure until the start of treatment, which indicated that this species may not have a self-limiting nature. In addition, two of the patients experienced a poor response to antimonial or pentamidine therapy. Thus, either ATL cases due to L. (V.) naiffi cannot be as uncommon as previously thought or this species is currently expanding in this region.
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