Evidence map›Paper›PMID 26517394›Full record

ArticleJournal of the American Chemical Society2015

Organization and Dynamics of Receptor Proteins in a Plasma Membrane.

Heidi Koldsø, Mark S P Sansom

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Impact of aging on the GABAbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Assembly and Analysis of Cell-Scale Membrane Envelopes.Journal of chemical information and modeling · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Computational Modeling of Claudin Structure and Function.International journal of molecular sciences · 2020
    Review
  17. Review
  18. Whole-Cell Models and Simulations in Molecular Detail.Annual review of cell and developmental biology · 2019
    Review
  19. Essay on Biomembrane Structure.The Journal of membrane biology · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Heidi KoldsøDepartment of Biochemistry, University of Oxford , South Parks Road, Oxford OX1 3QU, United Kingdom.
Mark S P SansomDepartment of Biochemistry, University of Oxford , South Parks Road, Oxford OX1 3QU, United Kingdom.

Funding

Biotechnology and Biological Sciences Research CouncilWellcome Trust
6 · The paper itself

Abstract

The interactions of membrane proteins are influenced by their lipid environment, with key lipid species able to regulate membrane protein function. Advances in high-resolution microscopy can reveal the organization and dynamics of proteins and lipids within living cells at resolutions <200 nm. Parallel advances in molecular simulations provide near-atomic-resolution models of the dynamics of the organization of membranes of in vivo-like complexity. We explore the dynamics of proteins and lipids in crowded and complex plasma membrane models, thereby closing the gap in length and complexity between computations and experiments. Our simulations provide insights into the mutual interplay between lipids and proteins in determining mesoscale (20-100 nm) fluctuations of the bilayer, and in enabling oligomerization and clustering of membrane proteins.

Indexed as

Membrane ProteinsMolecular Dynamics SimulationProtein BindingMembrane Proteins

Identifiers

PMID26517394
PMCPMC5591644

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.