ArticleToxins2015
Quantitative Detection of Shiga Toxins Directly from Stool Specimens of Patients Associated with an Outbreak of Enterohemorrhagic Escherichia coli in Japan--Quantitative Shiga toxin detection from stool during EHEC outbreak.
Article in Toxins, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Phylogenomic framework and virulence gene boundaries of emerging Shiga toxin-producingVirulence · 2026Article
- Shiga Toxin-ProducingMicroorganisms · 2025Review
- PathogenicFoods (Basel, Switzerland) · 2023Review
- Characterization of the Lytic Phage Flora With a Broad Host Range Against Multidrug-ResistantFrontiers in veterinary science · 2022Article
- Molecular Detection, Serotyping, and Antibiotic Resistance of Shiga ToxigenicAntibiotics (Basel, Switzerland) · 2021Article
- Article
- Stable Neutralization of a Virulence Factor in Bacteria Using Temperate Phage in the Mammalian Gut.mSystems · 2020Article
- Occurrence and quantification of Shiga toxin-producingVeterinary world · 2018Article
- Isolation and Characterization of phiLLS, a Novel Phage with Potential Biocontrol Agent against Multidrug-ResistantFrontiers in microbiology · 2017Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detection of Shiga toxins (Stx) is important for accurate diagnosis of Enterohemorrhagic Escherichia coli infection. In this study, we quantitatively analyzed Stx protein in nine patients' stool during an outbreak that occurred in Japan. Highly sensitive immunoassay (bead enzyme-linked immunosorbent assay (bead-ELISA)) revealed that the concentrations of toxins in stool of patients ranged from 0.71 to 10.44 ng/mL for Stx1 and 2.75 to 51.61 ng/mL for Stx2. To our knowledge, this is the first report that reveals the range of Stx protein concentrations in human stools.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.