ReviewMarine drugs2015
Chitosanases from Family 46 of Glycoside Hydrolases: From Proteins to Phenotypes.
Review in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 77 citations in OpenAlex.
- Nanoparticle Clearance and New Horizons in Engineered Drug Delivery.Pharmaceutics · 2026Review
- Integrative phylogenomic and pangenome landscape of Bacillus: insights from 10,000 genomes into taxonomy, functional potential, and biotechnological applications.World journal of microbiology & biotechnology · 2026Article
- Comparative Review of Microbial Chitosanases: Properties, Structures, Hydrolytic Modes and Applications.Current microbiology · 2026Review
- Targeting Non-ACS omega · 2025Article
- Improved Enzymatic Properties of Chitosanase CsnMY002 fromInternational journal of molecular sciences · 2025Article
- Expression of chitosanase from Aspergillus fumigatus chitosanase in Saccharomyces cerevisiae by CRISPR-Cas9 tools.Bioresources and bioprocessing · 2024Article
- Article
- Characterization of 5'-nucleotidases secreted from Streptomyces.Applied microbiology and biotechnology · 2023Article
- Insights into promiscuous chitosanases: the known and the unknown.Applied microbiology and biotechnology · 2022Review
- The Astounding World of Glycans from Giant Viruses.Chemical reviews · 2022Review
- Biodegradation and Prospect of Polysaccharide from Crustaceans.Marine drugs · 2022Review
- Biochemical characterization and cleavage pattern analysis of a novel chitosanase with cellulase activity.Applied microbiology and biotechnology · 2022Article
- Bifidobacterium castoris strains isolated from wild mice show evidence of frequent host switching and diverse carbohydrate metabolism potential.ISME communications · 2022Article
- Controllable preparation of chitosan oligosaccharidesFrontiers in microbiology · 2022Article
- Integrated Strategies for Enhancing the Expression of the AqCoA Chitosanase in Pichia pastoris by Combined Optimization of Molecular Chaperones Combinations and Copy Numbers via a Novel Plasmid pMC-GAP.Applied biochemistry and biotechnology · 2021Article
- Article
- Article
- Pilot-Scale Production of Chito-Oligosaccharides Using an Innovative Recombinant Chitosanase Preparation Approach.Polymers · 2021Article
- Heterologous Expression and Characterization of a High-Efficiency Chitosanase FromFrontiers in microbiology · 2021Article
- Overexpression and Biochemical Properties of a GH46 Chitosanase From MarineFrontiers in microbiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitosanases, enzymes that catalyze the endo-hydrolysis of glycolytic links in chitosan, are the subject of numerous studies as biotechnological tools to generate low molecular weight chitosan (LMWC) or chitosan oligosaccharides (CHOS) from native, high molecular weight chitosan. Glycoside hydrolases belonging to family GH46 are among the best-studied chitosanases, with four crystallography-derived structures available and more than forty enzymes studied at the biochemical level. They were also subjected to numerous site-directed mutagenesis studies, unraveling the molecular mechanisms of hydrolysis. This review is focused on the taxonomic distribution of GH46 proteins, their multi-modular character, the structure-function relationships and their biological functions in the host organisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.