Trial reportThe Angle orthodontist2015
Pain experience during initial alignment with three types of nickel-titanium archwires: a prospective clinical trial.
Trial report in The Angle orthodontist, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07474389 (A Split-mouth Randomized Controlled Trial Comparing Loupes-assisted Versus Conventional Bonding of Brackets in Terms of Discomfort and Bonding Duration in Crowded Dental Arches.), which is not on this map. Cited by 26 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Split-mouth Randomized Controlled Trial Comparing Loupes-assisted Versus Conventional Bonding of Brackets in Terms of Discomfort and Bonding Duration in Crowded Dental Arches.
Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Initial arch wires used in orthodontic treatment with fixed appliances.The Cochrane database of systematic reviews · 2024Pooled it
- Orthodontic treatment for crowded teeth in children.The Cochrane database of systematic reviews · 2021Pooled it
- Pain level between clear aligners and fixed appliances: a systematic review.Progress in orthodontics · 2020Pooled it
- Initial arch wires used in orthodontic treatment with fixed appliances.The Cochrane database of systematic reviews · 2018Pooled it
- [Relationship between initial archwire materials and pain at the initial stage of orthodontic treatment: a systematic review and network Meta-analysis].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2018Pooled it
- Analgesic Efficacy of Bromelain and Bromelain Plus Turmeric for Pain Control After Orthodontic Separator Placement: A Triple-Blind Randomized Clinical Trial.Clinical and experimental dental research · 2025Trial
- Tooth alignment and pain experience with A-NiTi versus Cu-NiTi: a randomized clinical trial.BMC oral health · 2021Trial
- Pain and discomfort during the first week of rapid maxillary expansion (RME) using two different RME appliances: A randomized controlled trial.The Angle orthodontist · 2017Trial
- Supplemental vibrational force does not reduce pain experience during initial alignment with fixed orthodontic appliances: a multicenter randomized clinical trial.Scientific reports · 2015Trial
- Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial.Progress in orthodontics · 2015Trial
- The effect of anterior bite turbos on pulpal blood flow and mobility of the lower central incisors and pain perception.The Angle orthodontist · 2026Article
- Dietary changes in patients with clear aligners compared with fixed orthodontic appliances during the early stages of orthodontic treatment: A systematic review.Korean journal of orthodontics · 2026Article
- Pain experience during initial alignment with self-ligating and conventional fixed orthodontic appliance system: A comparative clinical study.Journal of orthodontic science · 2026Article
- Comparative Assessment of Wire Deformation, Breakage, Frictional Resistance, and Patient Discomfort in Orthodontic Archwires: A Clinical Study.Journal of pharmacy & bioallied sciences · 2025Article
- Comparison of Initial Alignment Efficiency and Pain Perception of Three Copper-Nickel-Titanium Archwires of Different Manufacturers in Orthodontic Patients: A Randomized Clinical Trial.Journal of pharmacy & bioallied sciences · 2025Article
- Influence of orthodontic archwire (nickel-titanium versus copper-nickel-titanium) on pain in adult patients in the aligning phase of treatment with self-ligating brackets (two months of follow-up): a prospective observational pilot study.Head & face medicine · 2025Observational
- Impact of low-level laser therapy on orthodontic pain.Frontiers in neurology · 2025Article
- Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research.Heliyon · 2024Article
- Comparative analysis of periodontal pain and quality of life in patients with fixed multibracket appliances and aligners (Invisalign®): longitudinal clinical study.BMC oral health · 2023Article
- Bite Force, Occlusal Contact and Pain in Orthodontic Patients during Fixed-Appliance Treatment.Dentistry journal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo clinically evaluate the pain intensity during the week following initial placement of three different orthodontic aligning archwires. MATERIALS AND
methodsA consecutive sample of 75 patients requiring upper and lower fixed orthodontic appliances were alternately allocated into three different archwires (0.014-inch superelastic NiTi, 0.014-inch thermoelastic NiTi or 0.014-inch conventional NiTi). Assessments of pain/discomfort were made on a daily basis over the first 7-day period after bonding by means of visual analog scale and consumption of analgesics. The maximum pain score was recorded. The possible associations between age, gender, degree of crowding, and teeth irregularity and the pain intensity were also examined. Demographic and clinical differences between the three groups were compared with chi-square test or analysis of variance (ANOVA) test.
resultsNo statistically significant differences were found in the pain intensity when the three aligning NiTi archwires were compared (P = .63). No significant differences in pain perception were found in terms of gender, age, lower arch crowding, and incisor irregularity. The intake of analgesics was the least in the superelastic NiTi group.
conclusionThe three forms of NiTi wires were similar in terms of pain intensity during the initial aligning stage of orthodontic fixed appliance therapy. Gender, age, and the degree of crowding have no effect on the perceived discomfort experienced by patients undergoing fixed orthodontic treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.