Evidence map›Paper›PMID 26516427›Full record

ArticleWorld journal of radiology2015

Locoregional treatment for hepatocellular carcinoma: The best is yet to come.

Naveen Kalra, Pankaj Gupta, Yogesh Chawla, Niranjan Khandelwal

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05716620 (Utility of Abbreviated Magnetic Resonance Imaging as a Screening Tool for Hepatocellular Carcinoma in Cirrhotic Patients), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05716620 unknown statusnot on this mapstarted 2022, after this paper: background citation

Utility of Abbreviated Magnetic Resonance Imaging as a Screening Tool for Hepatocellular Carcinoma in Cirrhotic Patients

TypeobservationalSponsorPost Graduate Institute of Medical Education and Research, ChandigarhRan2022 to 2025Enrolled380ConditionsHepatocellular CarcinomaArmsMRI
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Naveen KalraNaveen Kalra, Pankaj Gupta, Niranjan Khandelwal, Deparment of Radiodiagnosis and Imaging, PGIMER, Chandigarh 160012, India.
Pankaj GuptaNaveen Kalra, Pankaj Gupta, Niranjan Khandelwal, Deparment of Radiodiagnosis and Imaging, PGIMER, Chandigarh 160012, India.
Yogesh ChawlaNaveen Kalra, Pankaj Gupta, Niranjan Khandelwal, Deparment of Radiodiagnosis and Imaging, PGIMER, Chandigarh 160012, India.
Niranjan KhandelwalNaveen Kalra, Pankaj Gupta, Niranjan Khandelwal, Deparment of Radiodiagnosis and Imaging, PGIMER, Chandigarh 160012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the sixth-most common type of cancer worldwide. The only definitive treatment modalities capable of achieving a cure are hepatic resection and hepatic transplantation. However, most patients are not candidates for these therapies. Overall, treatment options are driven by the stage of HCC. Early-stage disease is treated with ablative therapies, with radiofrequency ablation the ablative therapy of choice. Microwave ablation and irreversible electroporation are the other upcoming alternatives. Intermediate-stage disease is managed with transarterial chemoembolization (TACE), while advanced-stage disease is managed by sorafenib, with TACE and radioembolization as other alternatives.

Indexed as

Hepatocellular carcinomaHigh intensity focussed ultrasoundIrreversible electroporationMicrowave ablationRadiofrequency ablation

Identifiers

PMID26516427
PMCPMC4620111

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.