ArticleJournal of the American College of Cardiology2015
Cell Therapy Needs Rigorous Translational Studies in Large Animal Models.
Article in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Umbilical Cord Blood-Derived Cell Therapy for Perinatal Brain Injury: A Systematic Review & Meta-Analysis of Preclinical Studies.International journal of molecular sciences · 2023Pooled it
- Optimization of large animal MI models; a systematic analysis of control groups from preclinical studies.Scientific reports · 2017Pooled it
- Apoptotic bodies derived from human umbilical cord mesenchymal stem cells improve recovery from myocardial infarction in swine.Autophagy · 2026Article
- Human Umbilical Cord-Derived Cells Therapy for Hypoxic-Ischemic Encephalopathy: A Systematic Review and Meta-Analysis of Animal Models.International journal of pediatrics · 2025Article
- Endobronchial Aerosolized AAV1.SERCA2a Gene Therapy in a Pulmonary Hypertension Pig Model: Addressing the Lung Delivery Bottleneck.Human gene therapy · 2022Article
- MSC therapy in livestock models.Translational animal science · 2022Review
- iPSC Therapy for Myocardial Infarction in Large Animal Models: Land of Hope and Dreams.Biomedicines · 2021Review
- Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned.BMC cardiovascular disorders · 2021Article
- Combined meta-analysis of preclinical cell therapy studies shows overlapping effect modifiers for multiple diseases.BMJ open science · 2021Article
- Anesthesia Protocols used to Create Ischemia Reperfusion Myocardial Infarcts in Swine.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Review
- A realistic appraisal of the use of embryonic stem cell-based therapies for cardiac repair.European heart journal · 2020Article
- Optimization of Timing and Times for Administration of Atorvastatin-Pretreated Mesenchymal Stem Cells in a Preclinical Model of Acute Myocardial Infarction.Stem cells translational medicine · 2019Article
- A Basic Study of Photodynamic Therapy with Glucose-Conjugated Chlorin e6 Using Mammary Carcinoma Xenografts.Cancers · 2019Article
- Concise Review: The Regenerative Journey of Pericytes Toward Clinical Translation.Stem cells (Dayton, Ohio) · 2018Review
- Cortical Bone Stem Cells Administered at Reperfusion Attenuate Remote Zone Myocyte Remodeling.Circulation research · 2017Article
- Stem cells: Cell therapy for cardiac repair: what is needed to move forward?Nature reviews. Cardiology · 2017Article
- Targeting chronic cardiac remodeling with cardiac progenitor cells in a murine model of ischemia/reperfusion injury.PloS one · 2017Article
- A Large-Scale Investigation of Hypoxia-Preconditioned Allogeneic Mesenchymal Stem Cells for Myocardial Repair in Nonhuman Primates: Paracrine Activity Without Remuscularization.Circulation research · 2016Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.