ReviewLancet (London, England)2015
Turning off the tap: stopping tuberculosis transmission through active case-finding and prompt effective treatment.
Review in Lancet (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
120 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The asymptomatic tuberculosis proportion among the elderly population: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Facilitators and barriers to tuberculosis active case findings in low- and middle-income countries: a systematic review of qualitative research.BMC infectious diseases · 2023Pooled it
- Number Needed to Screen for Tuberculosis Disease Among Children: A Systematic Review.Pediatrics · 2023Pooled it
- Mortality in children diagnosed with tuberculosis: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2017Pooled it
- The Tuberculosis Cascade of Care in India's Public Sector: A Systematic Review and Meta-analysis.PLoS medicine · 2016Pooled it
- Community-based chest X-ray screening versus symptom-based case presentation in the elderly: evidence from three consecutive years of data.BMC geriatrics · 2026Article
- Spatiotemporal trends in tuberculosis incidence in Thailand, 2012-2023: a nationwide, province-level analysis.Infectious diseases of poverty · 2026Article
- Integrated surveillance of polio-negative acute flaccid paralysis cases for childhood tuberculosis: a novel GeneXpert-based screening approach in Rivers State, Nigeria.BMC infectious diseases · 2026Article
- Comparison of active and passive case finding on diagnostic delay and treatment outcomes in older patients with pulmonary tuberculosis: a cohort study using real-world data.BMC infectious diseases · 2026Article
- Measuring recent in-country TB transmission using a classification model with whole genome sequencing data.IJTLD open · 2026Article
- Article
- Sputum scarcity and associated factors in people undergoing tuberculosis testing in South Africa, Uganda, India, and the Philippines: an analysis of cross-sectional observational data.EClinicalMedicine · 2026Article
- Stakeholder engagement to identify barriers to implementation and inform the development of point-of-care diagnostics for TB.IJTLD open · 2026Article
- Integrating AI with PCR for Tuberculosis Diagnosis: Evaluating a Deep Learning Model for Chest X-Rays.Bioengineering (Basel, Switzerland) · 2025Article
- Adaptive bandit algorithms increase efficiency of mobile tuberculosis screening programs.Scientific reports · 2025Article
- Tuberculosis patients' delay in healthcare access and its associated factors in Shandong Province, China.BMC public health · 2025Article
- Barriers and Facilitators to Timely Diagnosis of Tuberculosis in Children and Adolescents in Karachi, Pakistan.International journal of environmental research and public health · 2025Article
- The potential impact, cost and cost-effectiveness of tuberculosis interventions - a modelling exercise.medRxiv : the preprint server for health sciences · 2025Article
- Alcohol Consumption of Male Tuberculosis Index Cases and Tuberculosis Transmission Among Social Contacts in Puducherry, India: A Cross-Sectional Analytical Study.Tropical medicine and infectious disease · 2025Article
- Implementation costs and cost-effectiveness of ultraportable chest X-ray with artificial intelligence in active case finding for tuberculosis in Nigeria.PLOS digital health · 2025Article
60 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
9 authors.
Funding
Abstract
To halt the global tuberculosis epidemic, transmission must be stopped to prevent new infections and new cases. Identification of individuals with tuberculosis and prompt initiation of effective treatment to rapidly render them non-infectious is crucial to this task. However, in settings of high tuberculosis burden, active case-finding is often not implemented, resulting in long delays in diagnosis and treatment. A range of strategies to find cases and ensure prompt and correct treatment have been shown to be effective in high tuberculosis-burden settings. The population-level effect of targeted active case-finding on reducing tuberculosis incidence has been shown by studies and projected by mathematical modelling. The inclusion of targeted active case-finding in a comprehensive epidemic-control strategy for tuberculosis should contribute substantially to a decrease in tuberculosis incidence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.