Evidence map›Paper›PMID 26514838›Full record

ArticleJournal of neurology2016

The neural correlates of motor intentional disorders in patients with subcortical vascular cognitive impairment.

Geon Ha Kim, Sang Won Seo, Kihyo Jung, Oh-Hun Kwon, Hunki Kwon, Jong Hun Kim, Jee Hoon Roh, Min-Jeong Kim, Byung Hwa Lee, Doo Sang Yoon and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Geon Ha KimDepartment of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.
Sang Won SeoDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kihyo JungSchool of Industrial Engineering, University of Ulsan, Ulsan, Korea.
Oh-Hun KwonDepartment of Biomedical Engineering, Hanyang University, Seoul, Korea.
Hunki KwonDepartment of Biomedical Engineering, Hanyang University, Seoul, Korea.
Jong Hun KimDepartment of Neurology, National Health Insurance Corporation, Ilsan Hospital, Goyang, Korea.
Jee Hoon RohDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Min-Jeong KimDepartment of Neurology, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Byung Hwa LeeDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Doo Sang YoonDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jung Won HwangSamsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Korea.
Jong Min LeeDepartment of Biomedical Engineering, Hanyang University, Seoul, Korea.
Jee Hyang JeongDepartment of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea.
Heecheon YouDepartment of Industrial and Management Engineering, Pohang University of Science and Technology, Pohang, Korea.
Kenneth M HeilmanDepartment of Neurology, University of Florida College of Medicine, and the Veterans Affairs Medical Center, Gainesville, FL, USA.
Duk L NaDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dukna@skku.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subcortical vascular cognitive impairment (SVCI) refers to cognitive impairment associated with small vessel disease. Motor intentional disorders (MID) have been reported in patients with SVCI. However, there are no studies exploring the neuroanatomical regions related to MID in SVCI patients. The aim of this study, therefore, was to investigate the neural correlates of MID in SVCI patients. Thirty-one patients with SVCI as well as 10 healthy match control participants were included. A "Pinch-Grip" apparatus was used to quantify the force control capabilities of the index finger in four different movement phases including initiation, development, maintenance, and termination. All participants underwent magnetic resonance imaging (MRI). Topographical cortical areas and white matter tracts correlated with the performances of the four different movement phases were assessed by the surface-based morphometry and tract-based spatial statistics analyses. Poorer performance in the maintenance task was related to cortical thinning in bilateral dorsolateral prefrontal, orbitofrontal and parietal cortices, while poorer performance in the termination task was associated with the disruption of fronto-parietal cortical areas as well as the white matter tracts including splenium and association fibers such as superior longitudinal fasciculus. Our study demonstrates that cortical areas and underlying white matter tracts associated with fronto-parietal attentional system play an important role in motor impersistence and perseveration in SVCI patients.

Indexed as

Cognitive DysfunctionIntentionAgedAged, 80 and overCerebral CortexCerebral Small Vessel DiseasesCorpus CallosumFemaleFingersHumansMagnetic Resonance ImagingMaleMiddle AgedMotor ActivityNeural PathwaysWhite MatterCortical thicknessMotor intentional disorderSubcortical vascular cognitive impairmentTract-based spatial statistics

Identifiers

PMID26514838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.