Evidence map›Paper›PMID 26514570›Full record

ArticleEnvironmental science and pollution research international2016

Metallothionein gene expression in embryos of the terrestrial snail (Cantareus aspersus) exposed to cadmium and copper in the Bordeaux mixture.

Pierre-Emmanuel Baurand, Reinhard Dallinger, Nicolas Capelli, Annette de Vaufleury

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Pierre-Emmanuel BaurandChrono-Environnement, UMR 6249 University of Bourgogne Franche-Comté, 16 route de Gray, 25000, Besançon, France.
Reinhard DallingerInstitute of Zoology, University of Innsbruck, Technikerstraße 25, 6020, Innsbruck, Austria.
Nicolas CapelliChrono-Environnement, UMR 6249 University of Bourgogne Franche-Comté, 16 route de Gray, 25000, Besançon, France.
Annette de VaufleuryChrono-Environnement, UMR 6249 University of Bourgogne Franche-Comté, 16 route de Gray, 25000, Besançon, France. annette.devaufleury@univ-fcomte.fr.
Laboratoire Chrono-Environnement · FRUniversität Innsbruck · AT

Funding

Austrian Science Fund FWF I 3032Austrian Science Fund FWF P 23635
6 · The paper itself

Abstract

The response specificity of three metallothionein (MT) genes (CdMT, CuMT and Cd/CuMT) was assessed after long-term exposure (20 days) of Cantareus aspersus eggs to cadmium (Cd) (2 to 6 mg/L) or to the fungicide Bordeaux mixture (BM) (2.5 and 7.5 g/L). MT gene expression measured by quantitative real-time PCR (qRT-PCR) revealed that in the unexposed embryos, the transcript levels of the three MT genes decreased significantly through embryonic development. However, the CdMT gene was strongly upregulated with increasing Cd exposure concentration, whereas the transcript levels of the other two genes increased less pronouncedly, but significantly above an exposure concentration of 4 mg Cd/L. Upon exposure to BM, all three MT genes were significantly upregulated above a BM concentration of 2.5 g/L. It is concluded that long-term Cd exposure in hatched snails induced patterns of MT gene expression that differed from those obtained after short-term exposure (24 h).

Indexed as

AnimalsCadmiumCopperDose-Response Relationship, DrugEmbryonic DevelopmentEmbryo, NonmammalianGene ExpressionMetallothioneinSnailsTime FactorsUp-RegulationBordeaux mixtureCadmiumCopperMetallothioneinBordeaux mixtureDetoxificationEmbryotoxicity

Identifiers

PMID26514570
OpenAlexW1930476885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.