Evidence map›Paper›PMID 26514567›Full record

ReviewEnvironmental science and pollution research international2015

Dioxin risk assessment: mechanisms of action and possible toxicity in human health.

Seyedeh Belin Tavakoly Sany, Rosli Hashim, Aishah Salleh, Majid Rezayi, David J Karlen, Bi Bi Marzieh Razavizadeh, Ebrahim Abouzari-Lotf

Abstract readReview
PubMed Publisher
In one paragraph

Review in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Review
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  7. Article
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  9. Article
  10. Review
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  12. Health Risk Assessment of Groundwater Contaminated by Oil Pollutants Based on Numerical Modeling.International journal of environmental research and public health · 2019
    Article
  13. Review
  14. Article
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  18. Review
  19. Triclosan exposure, transformation, and human health effects.Journal of toxicology and environmental health. Part B, Critical reviews · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seyedeh Belin Tavakoly SanyInstitute of Biological Sciences, University of Malaya, 50603, Kuala Lumpur, Malaysia. belintavakoli332@gmail.com.
Rosli HashimInstitute of Biological Sciences, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Aishah SallehInstitute of Biological Sciences, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Majid RezayiChemistry Department, Faculty of Science, University Malaya, 50603, Kuala Lumpur, Malaysia.
David J KarlenEnvironmental Protection Commission of Hillsborough County, 3629 Queen Palm Drive, Tampa, FL, 33619-1309, USA.
Bi Bi Marzieh RazavizadehDepartment of Food Chemistry, Research Institute of Food Science and Technology, P.O. Box: 91735-147, Mashhad, Iran.
Ebrahim Abouzari-LotfAdvanced Materials Research Group, Institute of Hydrogen Economy, Universiti Teknologi Malaysia, International Campus, 54100, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dioxin-like compounds (DLCs) have been classified by the World Health Organization (WHO) as one of the most persistent toxic chemical substances in the environment, and they are associated with several occupational activities and industrial accidents around the world. Since the end of the 1970s, these toxic chemicals have been banned because of their human toxicity potential, long half-life, wide dispersion, and they bioaccumulate in the food web. This review serves as a primer for environmental health professionals to provide guidance on short-term risk assessment of dioxin and to identify key findings for health and exposure assessment based on policies of different agencies. It also presents possible health effects of dioxins, mechanisms of action, toxic equivalency factors (TEFs), and dose-response characterization. Key studies related to toxicity values of dioxin-like compounds and their possible human health risk were identified through PubMed and supplemented with relevant studies characterized by reviewing the reference lists in the review articles and primary literature. Existing data decreases the scope of analyses and models in relevant studies to a manageable size by focusing on the set of important studies related to the perspective of developing toxicity values of DLCs.

Indexed as

AnimalsDioxinsEnvironmental ExposureHumansModels, AnimalRatsRisk AssessmentDioxinsDioxinsHumans risk assessment, AhR signaling, TEF approachToxicity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.