ArticleChemical senses2016
Changes in Olfactory Sensory Neuron Physiology and Olfactory Perceptual Learning After Odorant Exposure in Adult Mice.
Article in Chemical senses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Article
- Generalization of fear learning is shaped by inhibitory sensory processing in mice.Nature communications · 2026Article
- Imaging different cell populations in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight.Neurophotonics · 2024Review
- Decomposition of an odorant in olfactory perception and neural representation.Nature human behaviour · 2024Article
- The Role of the Stimulus in Olfactory Plasticity.Brain sciences · 2023Review
- Robust odor identification in novel olfactory environments in mice.Nature communications · 2023Article
- High trait anxiety blocks olfactory plasticity induced by aversive learning.Biological psychology · 2022Article
- NIH Workshop Report: sensory nutrition and disease.The American journal of clinical nutrition · 2021Article
- Stimulus Driven Functional Transformations in the Early Olfactory System.Frontiers in cellular neuroscience · 2021Article
- Sexually dimorphic behavioral and neural responses to a predator scent.Behavioural brain research · 2020Article
- Improved Separation of Odor Responses in Granule Cells of the Olfactory Bulb During Odor Discrimination Learning.Frontiers in cellular neuroscience · 2020Article
- Forever young: Neoteny, neurogenesis and a critique of critical periods in olfaction.Journal of bioenergetics and biomembranes · 2019Review
- The Value of Homework: Exposure to Odors in the Home Cage Enhances Odor-Discrimination Learning in Mice.Chemical senses · 2019Article
- Persistent, generalized hypersensitivity of olfactory bulb interneurons after olfactory fear generalization.Neurobiology of learning and memory · 2017Article
- Neuromodulation in Chemosensory Pathways.Chemical senses · 2017Review
- Differences in peripheral sensory input to the olfactory bulb between male and female mice.Scientific reports · 2017Article
- Amygdalar Gating of Early Sensory Processing through Interactions with Locus Coeruleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Article
- From rodents to humans: Rodent behavioral paradigms for social behavioral disorders.Brain circulationReview
- Lack of Pattern Separation in Sensory Inputs to the Olfactory Bulb during Perceptual Learning.eNeuroArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by testing mice in a cross-habituation/dishabituation behavioral paradigm before and after a week-long ester-odorant exposure protocol. In a parallel experiment, we used optical neurophysiology to observe neurotransmitter release from olfactory sensory neuron (OSN) terminals in vivo, and thus compared primary sensory representations of the aldehydes before and after the week-long ester-odorant exposure in individual animals. Mice could not discriminate between the aldehydes during pre-exposure testing, but ester-exposed subjects spontaneously discriminated between the homologous pair after exposure, whereas home cage control mice cross-habituated. Ester exposure did not alter the spatial pattern, peak magnitude, or odorant-selectivity of aldehyde-evoked OSN input to olfactory bulb glomeruli, but did alter the temporal dynamics of that input to make the time course of OSN input more dissimilar between odorants. Together, these findings demonstrate that odor exposure can induce both physiological and perceptual changes in odor processing, and suggest that changes in the temporal patterns of OSN input to olfactory bulb glomeruli could induce differences in odor quality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.