ReviewClinical reviews in allergy & immunology2017
The Clinical and Histological Spectrum of Idiopathic Inflammatory Myopathies.
Review in Clinical reviews in allergy & immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Multimodal ultrasound for precise quantitative evaluation of diaphragmatic lesions in idiopathic inflammatory myopathy: a promising assessment tool.Quantitative imaging in medicine and surgery · 2026Article
- Recognition of Idiopathic Inflammatory Myopathies Underlying Interstitial Lung Diseases.Diagnostics (Basel, Switzerland) · 2025Review
- Clinical, functional, and computed tomographic characterization of idiopathic inflammatory myopathy-associated interstitial lung disease: a retrospective cohort study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025Article
- Identification of hub glycolysis-related genes in acute myocardial infarction and their correlation with immune infiltration using bioinformatics analysis.BMC cardiovascular disorders · 2024Article
- Effect of Wei Qi Booster on immune and anti-oxidative function in aged mice.Frontiers in veterinary science · 2024Article
- Effects of saponins RbFrontiers in molecular biosciences · 2024Article
- Chest pain in a mid-aged woman, not simply myopericarditis: a case report of anti-Ku positive polymyositis.BMC cardiovascular disorders · 2021Article
- ALDOA protects cardiomyocytes against H/R-induced apoptosis and oxidative stress by regulating the VEGF/Notch 1/Jagged 1 pathway.Molecular and cellular biochemistry · 2021Article
- Dermatomyositis with exfoliation of esophageal mucosa: A case report.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Cardiovascular complications in patients with idiopathic inflammatory myopathies: does heart matter in idiopathic inflammatory myopathies?Heart failure reviews · 2021Review
- Underdiagnosis of cardiopulmonary involvement in patients with idiopathic inflammatory myopathies.Reumatologia · 2021Article
- Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis.EBioMedicine · 2020Article
- Panniculitis as an Initial Presentation of Dermatomyositis: A Case Report.JNMA; journal of the Nepal Medical Association · 2020Article
- Anterior segment parameters associated with extramuscular manifestations in polymyositis and dermatomyositis.International journal of ophthalmology · 2020Article
- Left Ventricular Deformation in Patients with Connective Tissue Disease: Evaluated by 3.0T Cardiac Magnetic Resonance Tissue Tracking.Scientific reports · 2019Article
- The spectrum and clinical significance of myositis-specific autoantibodies in Chinese patients with idiopathic inflammatory myopathies.Clinical rheumatology · 2019Article
- Clinical significance of myositis-specific autoantibody profiles in Japanese patients with polymyositis/dermatomyositis.Medicine · 2019Observational
- Autoimmunity in 2017.Clinical reviews in allergy & immunology · 2018Review
- Cutaneous Manifestations of Dermatomyositis: a Comprehensive Review.Clinical reviews in allergy & immunology · 2017Review
- Nailfold videocapillaroscopy and serum VEGF levels in scleroderma are associated with internal organ involvement.Auto- immunity highlights · 2016Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of myositis, characterised by chronic muscle weakness, cutaneous features, different extra-muscular manifestations and circulating autoantibodies. IIMs included classical polymyositis (PM), dermatomyositis (DM) and other different types of myositis with a wide range of muscle involvement. A complete autoantibody profile and a muscle biopsy are mandatory to correctly diagnose different clinical entities and to define their different prognosis. Bohan and Peter's criteria included five items to diagnose adult onset PM and DM. The sensitivity was 74-100 %, while the specificity is low, due to a poor ability to differentiate PM from neuromuscular diseases. Other criteria included a more accurate histological definition of PM, DM or amyopathic DM, obtaining a higher specificity. Autoantibodies' association, interstitial lung disease and clinical cardiac involvement represent the main items that could define the prognosis of these patients. On the other hand, inclusion body myositis is a different myopathy characterised by a peculiar muscle mass involvement, muscle atrophy and progressive loss of function, due to complete failure to all immunosuppressive drugs used. Treatment of IIMs is based on corticosteroids (CS), which show rapid clinical response and functional improvement. Different immunosuppressant drugs are given to obtain a better control of the disease during CS tapering dose. No controlled double blind trials demonstrated the superiority of one immunesuppressant on another. The occurrence of interstitial lung involvement requires the immediate introduction of immunosuppressants in addiction to CS. Severe dysphagia seems to improve with intravenous immunoglobulins (Ig). Physical therapy could be started after the acute phase of diseases and seems to have a beneficial role in muscle strength recovery.
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