ArticleEye (London, England)2016
Ultrastructure of medial rectus muscles in patients with intermittent exotropia.
Article in Eye (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pooled it
- Article
- Altered functional connectivity of resting-state networks and the correlation with clinical characteristics in intermittent exotropia adult patients: a resting-state magnetic resonance imaging study.BMC ophthalmology · 2024Article
- Distribution and appearance of myosin, dystrophin, and collagen IV in strabismus-affected extraocular muscle tissue compared with control tissue.The Journal of international medical research · 2024Observational
- Article
- Quantitative measurement of passive duction force tension in intermittent exotropia and its clinical implications.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Bilateral Occlusion Reduces the Ocular Deviation in Intermittent Exotropia.Investigative ophthalmology & visual science · 2021Article
- Decreased Functional Connectivity of the Primary Visual Cortex and the Correlation With Clinical Features in Patients With Intermittent Exotropia.Frontiers in neurology · 2021Article
- Comorbidity Networks in Cardiovascular Diseases.Frontiers in physiology · 2020Article
- Surgical management of intermittent exotropia: do we have an answer for all?BMJ open ophthalmology · 2019Review
- Incomitance and Eye Dominance in Intermittent Exotropia.Investigative ophthalmology & visual science · 2017Observational
- Ultrastructural pathological alterations in ocular muscles in a cat model with exotropia.International journal of clinical and experimental pathology · 2017Article
- Identification of rare paired box 3 variant in strabismus by whole exome sequencing.International journal of ophthalmology · 2017Article
- Assessment of Cortical Dysfunction in Patients with Intermittent Exotropia: An fMRI Study.PloS one · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PURPOSE To study the ultrastructure of the medial rectus in patients with intermittent exotropia at different ages.PATIENTS AND METHODS The medial recti were harvested surgically from 20 patients with intermittent exotropia. Patients were divided into adolescent (age<18 years, n=10) and adult groups (age >18 years, n=10). The normal control group included five patients without strabismus and undergoing eye enucleation. Hematoxylin and eosin staining and transmission electron microscopy were used to visualize the medial recti. Western blot was used to determine the levels of myosin and actin.RESULTS Varying fiber thickness, atrophy, and misalignment of the medial recti were visualized under optical microscope in patients with exotropia. Electron microscopy revealed sarcomere destruction, myofilament disintegration, unclear dark and light bands, collagen proliferation, and fibrosis. The adolescent group manifested significantly higher levels of myosin and actin than the adult group (P<0.05).CONCLUSION Younger patients with intermittent exotropia show stronger contraction of the medial recti compared with older patients. Our findings suggest that childhood was the appropriate time for surgery as the benefit of the intervention was better than in adulthood.
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