Evidence map›Paper›PMID 26513728›Full record

ArticleExperimental dermatology2016

Chemical chaperone therapy, a new strategy for genetic skin fragility disorders.

Jean Christopher Chamcheu, Imtiaz A Siddiqui, Hasan Mukhtar

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental dermatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Genotype-phenotype analysis of LMNA-related diseases predicts phenotype-selective alterations in lamin phosphorylation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jean Christopher ChamcheuDepartment of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Imtiaz A SiddiquiDepartment of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Hasan MukhtarDepartment of Dermatology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.

Funding

Targeting PI3K/Akt/mTOR for the management of psoriasisR01AR059742 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 2010 to 2019
$3.3M
Skin Diseases Research Center at the University of WisconsinP30AR066524 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI WOOD, GARY S · 2014 to 2018
$2.6M
NIAMS NIH HHS 1P30AR066524NIAMS NIH HHS P30 AR066524NIAMS NIH HHS R01 AR059742NIAMS NIH HHS R01AR059742
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular ChaperonesGenetic TherapyHumansKeratinsMutationKeratinsMolecular Chaperoneschemical chaperone-based therapygenetic skin diseaseskeratin gene mutationkeratin genodermatosesprotein misfoldingskin fragilitystress-induced keratin aggregation

Identifiers

PMID26513728
PMCPMC5697139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.