Evidence map›Paper›PMID 26513517›Full record

Trial reportPsychosomatic medicine2016

The Efficacy of Vigorous-Intensity Exercise as an Aid to Smoking Cessation in Adults With High Anxiety Sensitivity: A Randomized Controlled Trial.

Jasper A J Smits, Michael J Zvolensky, Michelle L Davis, David Rosenfield, Bess H Marcus, Timothy S Church, Mark B Powers, Georita M Frierson, Michael W Otto, Lindsey B Hopkins and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychosomatic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01065506 (Smoking Termination Enhancement Project), which is not on this map. Cited by 66 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01065506 phase3completednot on this map

Smoking Termination Enhancement Project (STEP)

TypeinterventionalSponsorSouthern Methodist UniversityRan2009 to 2013Enrolled150ConditionsSmokingArmsCognitive Behavioral Treatment, Nicotine Patch, Wellness Program, Aerobic Exercise
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  4. Exercise interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
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  16. Acute Effects of Aerobic Exercise on Affect and Smoking Craving in the Weeks Before and After a Cessation Attempt.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jasper A J SmitsFrom the Department of Psychology and Institute for Mental Health Research (Smits, Davis, Powers, Baird), The University of Texas at Austin, Austin, Texas; Department of Psychology (Zvolensky), University of Houston, Houston, Texas; Department of Behavioral Science (Zvolensky), The University of Texas MD Anderson Cancer Center, Houston, TX; Department of Psychology (Rosenfield), Southern Methodist University, Dallas, Texas; Department of Family & Preventive Medicine (Marcus), University of California at San Diego, San Diego, California; Pennington Biomedical Research Center (Church), Louisiana State University, Baton Rouge, Louisiana; Department of Psychology (Frierson), Howard University, Washington, DC; Departments of Psychology and Psychological and Brain Sciences (Otto), Boston University, Boston, Massachusetts; Stress and Health Research Program (Hopkins), San Francisco VA Medical Center, San Francisco, California; and School of Nursing (Brown), The University of Texas at Austin, Austin, Texas.
Michael J Zvolensky
Michelle L Davis
David Rosenfield
Bess H Marcus
Timothy S Church
Mark B Powers
Georita M Frierson
Michael W Otto
Lindsey B Hopkins
Richard A Brown
Scarlett O Baird

Funding

Exercise Intervention for SmokingR01DA027533 · NIDA · SOUTHERN METHODIST UNIVERSITY · PI ROSENFIELD, DAVID I, SMITS, JASPER · 2009 to 2012
$2.3M
NIDA NIH HHS R01 DA027533
6 · The paper itself

Abstract

objectivesHigh anxiety sensitivity predicts poor smoking cessation outcomes. Aerobic exercise reduces anxiety sensitivity and aspects of the risk conferred by anxiety sensitivity. In the current study, we examined whether exercise can aid smoking cessation in adults with high anxiety sensitivity.

methodsParticipants were sedentary and low-activity adult daily smokers (n = 136) with elevated prescreen anxiety sensitivity. Participants received 15 weeks of standard smoking cessation treatment (ST; cognitive behavioral therapy plus nicotine replacement therapy). In addition, participants were simultaneously randomized to 15 weeks of either an exercise intervention (ST + EX; n = 72) or a wellness education control condition (ST + CTRL; n = 64). Self-reported smoking abstinence was assessed weekly during the intervention, at the end of treatment (10 weeks after the target quit date), and at 4 and 6 months after the target quit date. Abstinence was verified by expired carbon monoxide readings and saliva cotinine.

resultsResults indicated that point prevalence abstinence (PPA) and prolonged abstinence (PA) rates were significantly higher for ST + EX than for ST + CTRL at each of the major end points among persons with high anxiety sensitivity (PPA: b = -0.91, standard error [SE] = 0.393, t(1171) = -2.33, p = .020; PA: b = -0.98, SE = 0.346, t(132) = -2.84, p = .005), but not among those with low anxiety sensitivity (PPA: b = -0.23, SE = 0.218, t(1171) = -1.06, p = .29; PA: b = -0.31, SE = 0.306, t(132) = -1.01, p = .32).

conclusionsThe present results suggest that exercise facilitates the odds of quit success for smokers with high levels of anxiety sensitivity and therefore may be a useful therapeutic tactic for this high-risk segment of the smoking population.

trial registrationClinicalTrials.gov, NCT01065506.

Indexed as

Outcome Assessment, Health CareSedentary BehaviorAdultAnxietyBreath TestsCognitive Behavioral TherapyCombined Modality TherapyExercise TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedSmoking CessationTobacco Use Cessation Devices

Identifiers

PMID26513517
PMCPMC4844851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.