Evidence map›Paper›PMID 26513453›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2016

Isolated proteinuria is a risk factor for pre-eclampsia: a retrospective analysis of the maternal and neonatal outcomes in women presenting with isolated gestational proteinuria.

S Shinar, J Asher-Landsberg, A Schwartz, M Ram-Weiner, M J Kupferminc, A Many

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Immunology of hepatic diseases during pregnancy.Seminars in immunopathology · 2016
    Review
  10. Association of hypoproteinemia in preeclampsia with maternal and perinatal outcomes: A retrospective analysis of high-risk women.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

S ShinarLis Maternity Hospital, Department of Obstetrics and Gynecology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
J Asher-LandsbergLis Maternity Hospital, Department of Obstetrics and Gynecology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
A SchwartzLis Maternity Hospital, Department of Obstetrics and Gynecology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
M Ram-WeinerLis Maternity Hospital, Department of Obstetrics and Gynecology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
M J KupfermincLis Maternity Hospital, Department of Obstetrics and Gynecology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
A ManyLis Maternity Hospital, Department of Obstetrics and Gynecology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv Sourasky Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine maternal and neonatal outcomes of isolated proteinuria and define maternal characteristics for progression to pre-eclampsia. STUDY

designRetrospective cohort study. Data from all hospitalized pregnant women between 2009 and 2014 with new onset isolated proteinuria of over 300 mg/24 h at admission were obtained. Follow-up was performed from the time of admission to the hospital to the time of discharge postpartum. Obstetrical, maternal and neonatal outcomes were obtained.

resultNinety-five pregnant women diagnosed with new onset isolated proteinuria were followed to term. Thirteen women developed pre-eclampsia during pregnancy and eight developed pre-eclampsia postpartum. Maternal characteristics for progression to pre-eclampsia were greater maximal values of proteinuria. Earlier pre-eclampsia onset was associated with early-onset proteinuria and multiple gestation. Although greater values of proteinuria were associated with increased risk for intrauterine growth restriction and lower Apgar scores, maternal outcome was favorable, regardless of pre-eclampsia progression. Isolated proteinuria progressing to pre-eclampsia was associated with late pre-eclampsia onset and favorable maternal and neonatal outcomes.

conclusionA significant proportion of women with new onset isolated proteinuria will develop pre-eclampsia. In these women, close follow-up is recommended until after delivery.

Indexed as

Pregnancy OutcomeAdultBlood PressureDatabases, FactualDisease ProgressionFemaleHumansInfant, NewbornIsraelLogistic ModelsMiddle AgedMultivariate AnalysisPre-EclampsiaPregnancyPregnancy ComplicationsProteinuria

Identifiers

PMID26513453
OpenAlexW1837470330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.