ArticlePLoS neglected tropical diseases2015
Influence of Schistosoma mansoni and Hookworm Infection Intensities on Anaemia in Ugandan Villages.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Prevalence and distribution of soil-transmitted helminth infections in Nigerian children: a systematic review and meta-analysis.Infectious diseases of poverty · 2018Pooled it
- The Efficacy of Single-Dose versus Double-Dose Praziquantel Treatments onBioMed research international · 2017Trial
- Bayesian machine learning enables discovery of risk factors for hepatosplenic multimorbidity related to schistosomiasis.Nature communications · 2026Article
- Getting back on track to meet global anaemia reduction targets: a Lancet Haematology Commission.The Lancet. Haematology · 2025Review
- Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda.Scientific reports · 2025Article
- Epidemiology of periportal fibrosis and relevance of current Schistosoma mansoni infection within the context of repeated mass drug administration in rural Uganda: a population-based, cross-sectional study.The Lancet. Microbe · 2024Article
- The short-term impact ofProceedings. Biological sciences · 2024Article
- Community-based deworming for hookworm benefits children treated within schools and is cost-effective due to economies of scale: the CoDe-STH trial.The Lancet regional health. Western Pacific · 2023Article
- Urinogenital schistosomiasis knowledge, attitude, practices, and its clinical correlates among communities along water bodies in the Kwahu Afram Plains North District, Ghana.PLoS neglected tropical diseases · 2023Article
- Prevalence of Intestinal Helminth Coinfection in Drug-Resistant Tuberculosis in Uganda.Open forum infectious diseases · 2022Article
- National surveillance of hookworm disease in China: A population study.PLoS neglected tropical diseases · 2022Article
- Diarrhoeal outcomes in young children depend on diarrhoeal cases of other household members: a cross-sectional study of 16,025 people in rural Uganda.BMC infectious diseases · 2022Article
- Iron Deficiency Anemia and Associated Factors Among Adolescent Girls and Women in a Rural Area of Jatinangor, Indonesia.International journal of women's health · 2022Article
- Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration.Nature communications · 2021Article
- Hookworm treatment induces a decrease of suppressive regulatory T cell associated with a Th2 inflammatory response.PloS one · 2021Article
- Schistosomes in the Lung: Immunobiology and Opportunity.Frontiers in immunology · 2021Review
- Prevalence and Associated Risk Factors of Intestinal Parasitic Infections among Pregnant Women Attending Antenatal Care in Yifag Health Center, Northwest Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021Article
- Article
- Impacts of host gender on Schistosoma mansoni risk in rural Uganda-A mixed-methods approach.PLoS neglected tropical diseases · 2020Article
- The division of labour between community medicine distributors influences the reach of mass drug administration: A cross-sectional study in rural Uganda.PLoS neglected tropical diseases · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundThe association of anaemia with intestinal schistosomiasis and hookworm infections are poorly explored in populations that are not limited to children or pregnant women.
methodsWe sampled 1,832 individuals aged 5-90 years from 30 communities in Mayuge District, Uganda. Demographic, village, and parasitological data were collected. Infection risk factors were compared in ordinal logistic regressions. Anaemia and infection intensities were analyzed in multilevel models, and population attributable fractions were estimated.
findingsHousehold and village-level predictors of Schistosoma mansoni and hookworm were opposite in direction or significant for single infections. S. mansoni was found primarily in children, whereas hookworm was prevalent amongst the elderly. Anaemia was more prevalent in individuals with S. mansoni and increased by 2.86 fold (p-value<0.001) with heavy S. mansoni infection intensity. Individuals with heavy hookworm were 1.65 times (p-value = 0.008) more likely to have anaemia than uninfected participants. Amongst individuals with heavy S. mansoni infection intensity, 32.0% (p-value<0.001) of anaemia could be attributed to S. mansoni. For people with heavy hookworm infections, 23.7% (p-value = 0.002) of anaemia could be attributed to hookworm. A greater fraction of anaemia (24.9%, p-value = 0.002) was attributable to heavy hookworm infections in adults (excluding pregnant women) as opposed to heavy hookworm infections in school-aged children and pregnant women (20.2%, p-value = 0.001).
conclusionCommunity-based surveys captured anaemia in children and adults affected by S. mansoni and hookworm infections. For areas endemic with schistosomiasis or hookworm infections, WHO guidelines should include adults for treatment in helminth control programmes.
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