Evidence map›Paper›PMID 26512712›Full record

Trial reportCancer2015

Group trajectory analysis helps to identify older cancer survivors who benefit from distance-based lifestyle interventions.

Miriam C Morey, Cindy K Blair, Richard Sloane, Harvey Jay Cohen, Denise C Snyder, Wendy Demark-Wahnefried

3 registry-linked trialsOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00037024 nacompletednot on this map

Project LEAD: Promoting Health Among Populations With Early Stage Cancers

TypeinterventionalSponsorDuke UniversityRan2002 to 2004ConditionsBreast Cancer, Depression, Fatigue, MalnutritionArmsfatigue assessment and management, nutritional support, physical therapy, psychosocial assessment and care, quality-of-life assessment
NCT00044980 nacompletednot on this map

Fresh Start: Promoting Health in Prostate Cancer Survivors

TypeinterventionalSponsorDuke UniversityRan2002 to 2006ConditionsMalnutrition, Prostate CancerArmsnutritional support, quality-of-life assessment
NCT00303875 phase2completednot on this map

RENEW: Reach Out to Enhance Wellness in Older Survivors

TypeinterventionalSponsorDuke UniversityRan2003 to 2009Enrolled641ConditionsBreast Cancer, Colorectal Cancer, Prostate CancerArmsbehavioral dietary and exercise intervention
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Systematic review and meta-analysis of maintenance of physical activity behaviour change in cancer survivors.The international journal of behavioral nutrition and physical activity · 2019
    Pooled it
  2. Trial
  3. Trial
  4. Physical activity and quality of life among breast cancer survivors: Pink SWAN.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Trajectory analysis in obesity epidemiology: a promising life course approach.Current opinion in endocrine and metabolic research · 2019
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Miriam C MoreyCenter for the Study of Aging/Claude D. Pepper Older Americans Independence Center, Duke University Medical Center, Durham, North Carolina.
Cindy K BlairDepartment of Internal Medicine, University of New Mexico, Albuquerque, New Mexico.
Richard SloaneCenter for the Study of Aging/Claude D. Pepper Older Americans Independence Center, Duke University Medical Center, Durham, North Carolina.
Harvey Jay CohenCenter for the Study of Aging/Claude D. Pepper Older Americans Independence Center, Duke University Medical Center, Durham, North Carolina.
Denise C SnyderSchool of Medicine, Duke University, Durham, North Carolina.
Wendy Demark-WahnefriedDepartment of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Duke University · USDuke Medical Center · USDuke University Hospital · USUniversity of Alabama at Birmingham · USUniversity of New Mexico · US

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Sarah B. Peskoe · 2006 to 2026
$24.6M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Harvest for Health in Older Cancer SurvivorsR01CA201362 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DEMARK-WAHNEFRIED, WENDY · 2016 to 2021
$2.8M
RENEW Research-out to ENhancE Wellness Older SurvivorsR01CA106919 · NCI · DUKE UNIVERSITY · PI DEMARK-WAHNEFRIED, WENDY · 2004 to 2007
$2.1M
NCI NIH HHS CA106919NCI NIH HHS R01 CA106919NCI NIH HHS R01 CA201362NIA NIH HHS P30 AG028716NIA NIH HHS P30AG028716NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

backgroundThe number of older cancer survivors is increasing as more adults survive to older ages. The objectives of this study were to examine trajectories of physical activity (PA) and physical function (PF) over a 2-year lifestyle counseling study and to identify characteristics of the trajectory groups.

methodsThis was a secondary analysis of Reach Out to Enhance Wellness, a randomized controlled trial of home-based lifestyle counseling. The 641 participants were older (≥65 years), overweight (body mass index [BMI], 25 to <40 kg/m(2)), long-term community-dwelling survivors (>5 years) of breast, prostate, and colorectal cancer from Canada, the United Kingdom, and the United States (21 states) who had been randomly assigned to an immediate intervention or a 12-month-wait-listed control arm. The main outcome measures were PA and PF trajectory group membership.

resultsThree PA groups and 5 PF trajectory groups were observed. The baseline BMI (P < .001) and self-efficacy for performing strength (P < .0001) and endurance exercises (P < .0002) were the strongest predictors of achieving the highest amount of PA and the most favorable functional trajectory over 2 years. Individuals with low baseline self-efficacy, no PA, and a Short Form 36 PF subscale score < 65 did not benefit from the intervention.

conclusionsThis study identified characteristics of survivors who benefited from home-based interventions and suggested alternative approaches for survivors requiring more structured and intensive interventions to promote behavioral changes.

Indexed as

Activities of Daily LivingMotor ActivityNeoplasmsRisk Reduction BehaviorSurvivorsTelephoneAgedBody Mass IndexBreast NeoplasmsCanadaColorectal NeoplasmsCounselingFemaleHumansMaleOverweightagedbreast neoplasmscolorectal neoplasmscounselingexercisehealth behaviorlifestyleprevention and controlprostatic neoplasmssurvivors

Identifiers

PMID26512712
PMCPMC4670587
OpenAlexW1857891535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.