ArticleToxins2015
Menadione-Induced Oxidative Stress Re-Shapes the Oxylipin Profile of Aspergillus flavus and Its Lifestyle.
Article in Toxins, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Effectiveness of Curcumin on Oxidative Stress in Goat Semen: Explorations Regarding Semen Quality, Sperm Apoptosis, Ultrastructure, and Markers of Oxidative Stress.Antioxidants (Basel, Switzerland) · 2025Article
- SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis ineLife · 2024Article
- New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging.Pharmaceutics · 2024Article
- Exploring Mechanisms of Antifungal Lipopeptide Iturin A from Bacillus againstJournal of fungi (Basel, Switzerland) · 2024Article
- Antifungal Activity of Essential Oil and Plant-Derived Natural Compounds againstAntibiotics (Basel, Switzerland) · 2022Review
- Superoxide Dismutases in Eukaryotic Microorganisms: Four Case Studies.Antioxidants (Basel, Switzerland) · 2022Review
- The Gβ-like ProteinJournal of fungi (Basel, Switzerland) · 2022Article
- The bZIP Ap1 transcription factor is a negative regulator of virulence attributes of the anthropophilic dermatophyteCurrent research in microbial sciences · 2022Article
- Menadione: a platform and a target to valuable compounds synthesis.Beilstein journal of organic chemistry · 2022Review
- Aflatoxins are natural scavengers of reactive oxygen species.Scientific reports · 2021Article
- Surviving the odds: From perception to survival of fungal phytopathogens under host-generated oxidative burst.Plant communications · 2021Review
- Antifungal Effects of Fusion Puroindoline B on the Surface and Intracellular Environment of Aspergillus flavus.Probiotics and antimicrobial proteins · 2021Article
- A Medium-Throughput System for In Vitro Oxidative Stress Assessment in IPEC-J2 Cells.International journal of molecular sciences · 2020Article
- Tramesan Elicits Durum Wheat Defense against the Septoria Disease Complex.Biomolecules · 2020Article
- Alternative Oxidase: A Potential Target for Controlling Aflatoxin Contamination and Propagation ofFrontiers in microbiology · 2020Review
- Use of Dual RNA-seq for Systems Biology Analysis ofFrontiers in microbiology · 2020Article
- Inhibition of Aflatoxin Production by Paraquat and External Superoxide Dismutase in Aspergillus flavus.Toxins · 2019Article
- Buckwheat Hull Extracts InhibitFrontiers in microbiology · 2019Article
- Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects.PloS one · 2017Article
- Functional Genomic Analysis of Aspergillus flavus Interacting with Resistant and Susceptible Peanut.Toxins · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillus flavus is an efficient producer of mycotoxins, particularly aflatoxin B₁, probably the most hepatocarcinogenic naturally-occurring compound. Although the inducing agents of toxin synthesis are not unanimously identified, there is evidence that oxidative stress is one of the main actors in play. In our study, we use menadione, a quinone extensively implemented in studies on ROS response in animal cells, for causing stress to A. flavus. For uncovering the molecular determinants that drive A. flavus in challenging oxidative stress conditions, we have evaluated a wide spectrum of several different parameters, ranging from metabolic (ROS and oxylipin profile) to transcriptional analysis (RNA-seq). There emerges a scenario in which A. flavus activates several metabolic processes under oxidative stress conditions for limiting the ROS-associated detrimental effects, as well as for triggering adaptive and escape strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.