Evidence map›Paper›PMID 26512631›Full record

ArticleGut microbes2015

Microbial signatures in post-infectious irritable bowel syndrome--toward patient stratification for improved diagnostics and treatment.

Jonna Jalanka, Anne Salonen, Susana Fuentes, Willem M de Vos

Registry-linked trialAbstract read
In one paragraph

Article in Gut microbes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05083091 (Smartphone Stress Management Training for Irritable Bowel Syndrome), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05083091 nacompletednot on this mapstarted 2022, after this paper: background citation

Smartphone Stress Management Training for Irritable Bowel Syndrome

TypeinterventionalSponsorCarnegie Mellon UniversityRan2022 to 2025Enrolled359ConditionsIrritable Bowel SyndromeArmsMindfulness and Attention Training, Mindfulness training, Coping Condition
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Efficacy and safety of probiotics in irritable bowel syndrome: A systematic review and meta-analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
  4. Five-Day Treatment withNutrients · 2025
    Trial
  5. Trial
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Post-infection Irritable Bowel Syndrome.Gastroenterology clinics of North America · 2021
    Review
  17. Article
  18. Observational
  19. Clinical Management of the Microbiome in Irritable Bowel Syndrome.Journal of the Canadian Association of Gastroenterology · 2021
    Article
  20. Role of Inflammation in Pathophysiology of Colonic Disease: An Update.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonna Jalankaa Department of Veterinary Biosciences ; Microbiology; University of Helsinki ; Helsinki , Finland.
Anne Salonenb Department of Bacteriology and Immunology ; Immunobiology Research Program; University of Helsinki ; Helsinki , Finland.
Susana Fuentesc Laboratory of Microbiology; Wageningen University ; Wageningen , The Netherlands.
Willem M de Vosa Department of Veterinary Biosciences ; Microbiology; University of Helsinki ; Helsinki , Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome (IBS) is a multifactorial and heterogeneous disorder estimated to affect over 10% of the Western population. A subset of the patients reports the start of the disease after an episode of gastroenteritis. The alterations in the intestinal microbiota of the post-infectious IBS (PI-IBS) patients were recently investigated in a British cohort and shown to differentiate from the healthy controls and resemble that of diarrhea-predominant IBS (IBS-D) patients. The altered 27 genus-like groups created a microbial signature, which could be used to objectively stratify patients and healthy controls. In this addendum, we combine the microbiota data derived from the British cohort with that of a recently reported Swedish PI-IBS cohort. Remarkably, robust and reproducible microbiota signatures were observed in these PI-IBS patients. We discuss these results with attention on the emerging role of microbiota in the classification, development and treatment of PI-IBS.

Indexed as

FecesGene ExpressionHumansIntestinal MucosaIrritable Bowel SyndromeMicrobiotaIMDirritable bowel syndromemicrobiotaPI-IBS

Identifiers

PMID26512631
PMCPMC4826089

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.