Observational studyMedicine2015
Current Epidemiology and Outcome of Infective Endocarditis: A Multicenter, Prospective, Cohort Study.
Observational study in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 1 synthesis or guideline pooled it, 199 citations in OpenAlex.
- Prophylactic antibiotic use for infective endocarditis: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Article
- The geriatric syndromes in elderly patients with infective endocarditis: impact on in-hospital mortality.Journal of geriatric cardiology : JGC · 2026Article
- Disseminated Septic Emboli From Aortic Valve Infective Endocarditis in an Immunocompromised Patient: A Case Report.Cureus · 2026Article
- From bone replacement to regeneration. A biomaterials started journey.Materials today. Bio · 2026Review
- Infective Endocarditis: A Contemporary Review of Epidemiology, Diagnosis, and Management.Antibiotics (Basel, Switzerland) · 2026Review
- Low Yield of Blood Cultures After End of Therapy of an Episode of Infective Endocarditis: 12 Years' Experience From a Referral Center.Open forum infectious diseases · 2026Article
- Prosthetic Valve Endocarditis-Insights from the NatIonal Danish Endocarditis stUdieS (NIDUS) Registry.Diagnostics (Basel, Switzerland) · 2026Article
- Prognosis of Infective Endocarditis According to Clinical Characteristics, Economic Status, and Center Experience.Yonsei medical journal · 2026Article
- Exploring mesenchymal stem cells as a novel therapeutic approach for HACEK endocarditis: a narrative review.Journal of cardiothoracic surgery · 2026Review
- Annular reconstruction in infective endocarditis: Comparative analysis of surgical outcomes and infection recurrence.Medicine · 2026Observational
- Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis.Nature communications · 2026Article
- From structural heart lesions to host burden: changing epidemiology and outcomes of native valve infective endocarditis, a nationwide study, 2006-2023.Open heart · 2026Article
- Trends and disparities in mortality from infective endocarditis in the United States, 1999-2023: a nationwide analysis.Frontiers in cardiovascular medicine · 2026Article
- Infective endocarditis in the real world: Diagnostic challenges and predictors of in-hospital mortality in a 10-year retrospective cohort from a Brazilian tertiary center.Revista do Instituto de Medicina Tropical de Sao Paulo · 2026Article
- [Contemporary management of endocarditis].Herz · 2025Review
- Fewer Minor Modified Duke Criteria on Admission Are Associated with Worse 90-Day Mortality in Patients with Confirmed Infective Endocarditis.Journal of clinical medicine · 2025Article
- Sex differences in a murine model of infective endocarditis.Basic research in cardiology · 2025Article
- Article
- Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to describe the epidemiologic and clinical characteristics and identify the risk factors of short-term and 1-year mortality in a recent cohort of patients with infective endocarditis (IE).From January 2008, multidisciplinary teams have prospectively collected all consecutive cases of IE, diagnosed according to the Duke criteria, in 25 Spanish hospitals.Overall, 1804 patients were diagnosed. The median age was 69 years (interquartile range, 55-77), 68.0% were men, and 37.1% of the cases were nosocomial or health care-related IE. Gram-positive microorganisms accounted for 79.3% of the episodes, followed by Gram-negative (5.2%), fungi (2.4%), anaerobes (0.9%), polymicrobial infections (1.9%), and unknown etiology (9.1%). Heart surgery was performed in 44.2%, and in-hospital mortality was 28.8%. Risk factors for in-hospital mortality were age, previous heart surgery, cerebrovascular disease, atrial fibrillation, Staphylococcus or Candida etiology, intracardiac complications, heart failure, and septic shock. The 1-year independent risk factors for mortality were age (odds ratio [OR], 1.02), neoplasia (OR, 2.46), renal insufficiency (OR, 1.59), and heart failure (OR, 4.42). Surgery was an independent protective factor for 1-year mortality (OR, 0.44).IE remains a severe disease with a high rate of in-hospital (28.9%) and 1-year mortality (11.2%). Surgery was the only intervention that significantly reduced 1-year mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.