Evidence map›Paper›PMID 26512294›Full record

ArticleAnnals of general psychiatry2015

Identification of hypertensive patients with dominant affective temperaments might improve the psychopathological and cardiovascular risk stratification: a pilot, case-control study.

Andrea László, Levente Babos, Zsóka Kis-Igari, Adrienn Pálfy, Péter Torzsa, Ajándék Eőry, László Kalabay, Xenia Gonda, Zoltán Rihmer, Orsolya Cseprekál and 5 more

Open access · goldAbstract read
In one paragraph

Article in Annals of general psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Andrea LászlóDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
Levente BabosDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
Zsóka Kis-IgariDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
Adrienn PálfyDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
Péter TorzsaDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
Ajándék EőryDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
László KalabayDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary.
Xenia GondaDepartment of Pharmacodynamics, Semmelweis University Budapest, Budapest, Hungary ; Department of Clinical and Theoretical Mental Health, Semmelweis University Budapest, Budapest, Hungary ; MTA-SE Neurochemistry Research Group, Budapest, Hungary.ORCID 0000-0001-9015-4203
Zoltán RihmerDepartment of Clinical and Theoretical Mental Health, Semmelweis University Budapest, Budapest, Hungary.
Orsolya CseprekálIst Department of Internal Medicine, Budapest, Hungary.
András TislérIst Department of Internal Medicine, Budapest, Hungary.
Judit HodreaMTA-SE "Lendület" Diabetes Research Group Budapest, Budapest, Hungary.
Lilla LénártMTA-SE "Lendület" Diabetes Research Group Budapest, Budapest, Hungary.
Andrea FeketeMTA-SE "Lendület" Diabetes Research Group Budapest, Budapest, Hungary.
János NemcsikDepartment of Family Medicine, Semmelweis University Budapest, Budapest, Hungary ; Health Service of Zugló (ZESZ), Budapest, Hungary.
Semmelweis University · HUMontavid Thermodynamic Research Group · HUMagyar Agrár- és Élettudományi Egyetem · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough mood disorders and cardiovascular diseases have widely studied psychosomatic connections, data concerning the influence of the psychopathologically important affective temperaments in hypertension are scarce. To define a possibly higher cardiovascular risk subpopulation we investigated in well-treated hypertensive patients with dominant affective temperaments (DOM) and in well-treated hypertensive patients without dominant temperaments the level of depression and anxiety, arterial stiffness and serum Brain-derived Neurotrophic Factor (seBDNF).

methods175 hypertensive patients, free of the history of psychiatric diseases, completed the TEMPS-A, Beck Depression Inventory and Hamilton Anxiety Scale questionnaires in two primary care practices. Of those 175 patients, 24 DOM patients and 24 hypertensive controls (matched in age, sex and the presence of diabetes) were selected for measurements of arterial stiffness and seBDNF level.

resultsBeck and Hamilton scores in DOM patients were higher compared with controls. Pulse wave velocity and augmentation index did not differ between the groups while in the DOM patients decreased brachial systolic and diastolic and central diastolic blood pressures were found compared with controls. SeBDNF was lower in the DOM group than in the controls (22.4 ± 7.2 vs. 27.3 ± 7.8 ng/mL, p < 0.05).

conclusionsAlthough similar arterial stiffness parameters were found in DOM patients, their increased depression and anxiety scores, the decreased brachial and central diastolic blood pressures as well as the decreased seBDNF might refer to their higher vulnerability regarding the development not only of major mood disorders, but also of cardiovascular complications. These data suggest that the evaluation of affective temperaments should get more attention both with regard to psychopathology and cardiovascular health management.

Indexed as

Affective temperamentsAnxietyArterial stiffnessBrain-derived neurotrophic factorCardiovascular riskDepressionHypertension

Identifiers

PMID26512294
PMCPMC4623904
OpenAlexW2170153948

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.