Evidence map›Paper›PMID 26512172›Full record

ArticleAnnals of dermatology2015

Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part II): Systemic Treatment.

Jung Eun Kim, Hyun Jeong Kim, Bark-Lynn Lew, Kyung Ho Lee, Seung Phil Hong, Yong Hyun Jang, Kui Young Park, Seong Jun Seo, Jung Min Bae, Eung Ho Choi and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Annals of dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
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  5. Article
  6. Efficacy and Potential Mechanisms of Naringin in Atopic Dermatitis.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 16 institutions in 2 countries.

Jung Eun KimDepartment of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyun Jeong KimDepartment of Dermatology, Seoul Medical Center, Seoul, Korea.
Bark-Lynn LewDepartment of Dermatology, Kyung Hee University College of Medicine, Seoul, Korea.
Kyung Ho LeeDepartment of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seung Phil HongDepartment of Dermatology, Dankook University Medical College, Cheonan, Korea.
Yong Hyun JangDepartment of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
Kui Young ParkDepartment of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
Seong Jun SeoDepartment of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
Jung Min BaeDepartment of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Eung Ho ChoiDepartment of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.
Ki Beom SuhrDepartment of Dermatology, SA Dermatology Clinic, Daejeon, Korea.
Seung Chul LeeDepartment of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
Hyun Chang KoDepartment of Dermatology, Pusan National University School of Medicine, Busan, Korea.
Young Lip ParkDepartment of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
Sang Wook SonDepartment of Dermatology, Korea University College of Medicine, Seoul, Korea.
Young Jun SeoDepartment of Dermatology, Chungnam National University College of Medicine, Daejeon, Korea.
Yang Won LeeDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
Sang Hyun ChoDepartment of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chun Wook ParkDepartment of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
Joo Young RohDepartment of Dermatology, Gachon University Gil Medical Center, Incheon, Korea.
Catholic University of Korea · KRChung-Ang University · KRChonnam National University Hospital · KRChungnam National University · KRDankook University · KRGachon University Gil Medical Center · KRHallym University Kangnam Sacred Heart Hospital · KRKonkuk University · KRKorea University · KRKyung Hee University · KRKyungpook National University · KRPusan National University · KRSeoul Medical Center · KRSoonchunhyang University · KRUniversity Dermatology · USYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the treatment guidelines for atopic dermatitis (AD) were issued by the Korean Atopic Dermatitis Association (KADA) work group in 2006, there have been further advances in the systemic treatment of AD.

objectiveWe aimed to establish updated evidence- and experience-based systemic treatment guidelines for Korean AD.

methodsWe compiled a database of references from relevant systematic reviews and guidelines regarding the systemic management of AD, including antihistamines, antimicrobials, systemic immunomodulators, allergen-specific immunotherapy, phototherapy, adjunctive treatment, and complementary and alternative medicines. Evidence for each statement was graded and classified based on the strength of the recommendation. Thirty-nine council members of KADA participated in the three rounds of votes and expert consensus recommendations were established.

resultsThe use of antihistamines is recommended to relieve pruritus and to prevent exacerbation due to scratching in AD patients. Infection should be controlled as needed and long-term medication should be avoided. For moderate to severe AD patients, concomitant active treatments with systemic immunomodulators are indicated. Cyclosporine is the first choice among systemic immunomodulators and others should be considered as second-line alternatives. Allergen-specific immunotherapy could be effective in AD patients with aeroallergen hypersensitivity. Phototherapy can be useful for moderate to severe AD patients and narrow-band ultraviolet B is the most effective option. Complementary and alternative medicines cannot be recommended for treating AD.

conclusionWe expect these recommendations to be a reference guide for physicians and AD patients in choosing the appropriate treatment to improve quality of life and decrease unnecessary social medical costs.

Indexed as

AdministrationDermatitisGuidelineKoreaoralTherapeutics

Identifiers

PMID26512172
PMCPMC4622892
OpenAlexW1940572799

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.