ArticleJournal of experimental botany2016
Major latex protein-like protein 43 (MLP43) functions as a positive regulator during abscisic acid responses and confers drought tolerance in Arabidopsis thaliana.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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60 citing papers in PubMed, 143 citations in OpenAlex.
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- Characterization of the major latex protein gene family and functional analysis ofFrontiers in plant science · 2026Article
- Overexpression of a major latex-like protein from wild Arachis (AdMLP11) confers tolerance to recurrent drought stress.Genetics and molecular biology · 2026Article
- Genome-wide analysis of soybean MLPs reveals evolutionary and structural insights into drought, salt stress and ABA responses.BMC plant biology · 2025Article
- Green Synthesized Titanium Oxide Nanoparticles Promote Salt Tolerance in Soybean.International journal of molecular sciences · 2025Article
- Differential gene reactions reveal drought response strategies in African acacias.The Plant journal : for cell and molecular biology · 2025Article
- Enhanced drought and salt stress tolerance in Arabidopsis via ectopic expression of the PvMLP19 gene.Plant cell reports · 2025Article
- SnRK2s: Kinases or Substrates?Plants (Basel, Switzerland) · 2025Review
- A Major Latex Protein-Encoding Gene fromInternational journal of molecular sciences · 2025Article
- Identification of two QTLs for web blotch resistance in peanut (Arachis hypogaea L.) based on BSA-seq.BMC plant biology · 2024Article
- Effect of berry maturity stages on the germination and protein constituents of African nightshade (Solanum scabrum) seeds.Scientific reports · 2024Article
- Heterologous expression of Halostachys caspica pathogenesis-related protein 10 increases salt and drought resistance in transgenic Arabidopsis thaliana.Plant molecular biology · 2024Article
- Exploring the Genetic Basis of Drought Tolerance inInternational journal of molecular sciences · 2024Article
- A Comprehensive Analysis of the 9-Cis Epoxy Carotenoid Dioxygenase Gene Family and Their Responses to Salt Stress inPlants (Basel, Switzerland) · 2024Article
- Transcriptomic landscape of seedstick in Arabidopsis thaliana funiculus after fertilisation.BMC plant biology · 2024Article
- Article
- Genome-Wide Characterization and Expression Analyses of Major Latex Protein Gene Family inInternational journal of molecular sciences · 2024Article
- Identification and analysis of major latex protein (Frontiers in plant science · 2024Article
- Genome-Wide Evolutionary Characterization and Expression Analysis of Major Latex Protein (MLP) Family Genes in Tomato.International journal of molecular sciences · 2023Article
- Major latex-like proteins show pH dependency in their binding to hydrophobic organic pollutants.Journal of pesticide science · 2023Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drought stress is one of the disadvantageous environmental conditions for plant growth and reproduction. Given the importance of abscisic acid (ABA) to plant growth and abiotic stress responses, identification of novel components involved in ABA signalling transduction is critical. In this study, we screened numerous Arabidopsis thaliana mutants by seed germination assay and identified a mutant mlp43 (major latex protein-like 43) with decreased ABA sensitivity in seed germination. The mlp43 mutant was sensitive to drought stress while the MLP43-overexpressed transgenic plants were drought tolerant. The tissue-specific expression pattern analysis showed that MLP43 was predominantly expressed in cotyledons, primary roots and apical meristems, and a subcellular localization study indicated that MLP43 was localized in the nucleus and cytoplasm. Physiological and biochemical analyses indicated that MLP43 functioned as a positive regulator in ABA- and drought-stress responses in Arabidopsis through regulating water loss efficiency, electrolyte leakage, ROS levels, and as well as ABA-responsive gene expression. Moreover, metabolite profiling analysis indicated that MLP43 could modulate the production of primary metabolites under drought stress conditions. Reconstitution of ABA signalling components in Arabidopsis protoplasts indicated that MLP43 was involved in ABA signalling transduction and acted upstream of SnRK2s by directly interacting with SnRK2.6 and ABF1 in a yeast two-hybrid assay. Moreover, ABA and drought stress down-regulated MLP43 expression as a negative feedback loop regulation to the performance of MLP43 in ABA and drought stress responses. Therefore, this study provided new insights for interpretation of physiological and molecular mechanisms of Arabidopsis MLP43 mediating ABA signalling transduction and drought stress responses.
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