ArticleBiological research for nursing2016
CRH as a Predictor of Preterm Birth in Minority Women.
Article in Biological research for nursing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Neonatal Hair Cortisol and Birth Outcomes: An Empirical Study and Meta-Analysis.Psychosomatic medicine · 2024Pooled it
- Maternal mycoestrogen exposure in relation to timing of birth and placental corticotropin releasing hormone concentrations in a U.S. pregnancy cohort.Reproductive toxicology (Elmsford, N.Y.) · 2026Article
- The Association of Perceived Stress, Glucocorticoids Receptors, and Corticotropin-Releasing Hormone Gene Expression During Pregnancy.Biological research for nursing · 2025Article
- Stress-induced developmental plasticity and spontaneous preterm birth: A justice-oriented eco-evo-devo review.European journal of obstetrics & gynecology and reproductive biology: X · 2025Review
- Psychosocial stress and associations with inflammation in mid-gestation maternal, fetal, and placental tissue.Reproductive toxicology (Elmsford, N.Y.) · 2025Article
- Sex-specific associations between placental corticotropin releasing hormone and problem behaviors in childhood.Psychoneuroendocrinology · 2024Article
- Impact of unplanned pregnancy on neonatal outcomes: findings of new high-risk newborns in Peru.International health · 2024Article
- A framework for testing pathways from prenatal stress-responsive hormones to cardiovascular disease risk.Frontiers in endocrinology · 2023Review
- The mastery lifestyle intervention to reduce biopsychosocial risks for pregnant Latinas and African Americans and their infants: protocol for a randomized controlled trial.BMC pregnancy and childbirth · 2022Article
- DNA Methylation Patterns of Glucocorticoid Pathway Genes in Preterm Birth Among Black Women.Biological research for nursing · 2022Article
- Maternal perceived stress and the increased risk of preterm birth in a majority non-Hispanic Black pregnancy cohort.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- The Association of Preterm Birth With Maternal Nativity and Length of Residence Among Non-Hispanic Black Women.CJC open · 2022Article
- Prenatal phthalate exposure in relation to placental corticotropin releasing hormone (pCRH) in the CANDLE cohort.Environment international · 2022Article
- Prenatal polycyclic aromatic hydrocarbon (PAH) exposure in relation to placental corticotropin releasing hormone (pCRH) in the CANDLE pregnancy cohort.Frontiers in endocrinology · 2022Article
- Effect of a Nonoptimal Cervicovaginal Microbiota and Psychosocial Stress on Recurrent Spontaneous Preterm Birth.American journal of perinatology · 2021Article
- Antepartum Depression and Preterm Birth: Pathophysiology, Epidemiology, and Disparities due to structural racism.Current psychiatry reports · 2021Review
- Placental CRH as a Signal of Pregnancy Adversity and Impact on Fetal Neurodevelopment.Frontiers in endocrinology · 2021Review
- Alterations in endogenous progesterone metabolism associated with spontaneous very preterm delivery.Human reproduction open · 2020Article
- Associations of Phthalates and Phthalate Replacements With CRH and Other Hormones Among Pregnant Women in Puerto Rico.Journal of the Endocrine Society · 2019Article
- Psychosocial Stress and Preterm Birth: The Impact of Parity and Race.Maternal and child health journal · 2018Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo determine the predictive capability of corticotropin-releasing hormone (CRH) as a biomarker of preterm birth (PTB) in minority women. STUDY
designVenous blood samples were obtained at 22-24 weeks' gestation in a prospective, descriptive study of 707 minority women experiencing low-risk pregnancies. CRH was analyzed using a radioimmunoassay and methanol extraction protocol.
resultCRH predicted PTB in both African American and Hispanic women. The odds ratio was 1.8 times greater for having a PTB if the CRH level was >24 pg/ml. The median CRH for African American women having a PTB was 46.6 pg/ml and for Hispanic women was 35.03 pg/ml. Using a receiver-operating characteristic curve, the threshold for CRH among the African American women was 30.6 pg/ml and among the Hispanic women was 27.4 pg/ml.
conclusionCRH may be an important biomarker for predicting PTB in minority women, especially when combined with other predictors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.