SynthesisJournal of endocrinological investigation2016
The correct renal function evaluation in patients with thyroid dysfunction.
Synthesis in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association Between Serum Cystatin C and Thyroid Diseases: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Current evidence on the use of anti-RAAS agents in congenital or acquired solitary kidney.Renal failure · 2017Pooled it
- An open-label, randomized, placebo-controlled study on the effectiveness of a novel probiotics administration protocol (ProbiotiCKD) in patients with mild renal insufficiency (stage 3a of CKD).European journal of nutrition · 2019Trial
- Cognitive impairment in CKD patients: a guidance document by the CONNECT network.Clinical kidney journal · 2025Review
- Myxedema Coma: A Grave Phenomenon Partially Reversed CKD Status With Treatment of Hypothyroidism.Cureus · 2023Article
- Impact of Thyroid Cancer Treatment on Renal Function: A Relevant Issue to Be Addressed.Journal of personalized medicine · 2023Review
- Association between Urinary Creatinine Excretion and Hypothyroidism in Patients with Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2023Article
- Minimal change disease associated with thyroid cancer: a case report.Frontiers in medicine · 2023Article
- Article
- Observational
- Masked CKD in hyperthyroidism and reversible CKD status in hypothyroidism.Frontiers in endocrinology · 2022Article
- Cystatin C, a Controversial Biomarker in Hypothyroid Patients under Levothyroxine Therapy: THYRenal, a Pilot Cohort Observational Study.Journal of clinical medicine · 2020Article
- Estimating glomerular filtration rate in children: evaluation of creatinine- and cystatin C-based equations.Pediatric nephrology (Berlin, Germany) · 2019Observational
- The diagnostic value of human epididymis protein 4 as a novel biomarker in patients with renal dysfunction.International urology and nephrology · 2018Article
- Impact of subclinical hypothyroidism with TSH ≤10 mIU/L on glomerular filtration rate in adult women without known kidney disease.Endocrine · 2018Article
- Estimating Glomerular Filtration Rate in Kidney Transplant Recipients: Comparing a Novel Equation With Commonly Used Equations in this Population.Transplantation direct · 2017Article
- Physical performance in newly diagnosed hypothyroidism: a pilot study.Journal of endocrinological investigation · 2017Article
- Rare Renal Diseases Can Be Used as Tools to Investigate Common Kidney Disorders.Kidney diseases (Basel, Switzerland) · 2017Review
- How to improve duration and efficiency of the antiproteinuric response to Ramipril: RamiPROT-a prospective cohort study.Journal of nephrology · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid dysfunction induces several renal derangements involving all nephron portions. Furthermore, dysthyroidism is a recognized risk factor associated with the development of chronic kidney disease. Current data, in fact, demonstrate that either subclinical or overt thyroid disease is associated with significant changes in creatinine, estimated glomerular filtration rate, measured glomerular filtration rate and Cystatin C. Herein, we systematically reviewed several relevant studies aiming at the identification of the most sensitive and specific parameter for the correct renal function evaluation in patients with thyroid dysfunction, that are usually treated as outpatients. Our systematic review indicates that estimated glomerular filtration rate, preferably with CKD-EPI equation, appears to be the most reliable and wieldy renal function parameter. Instead, Cystatin C should be better used in the grading of thyroid dysfunction severity.
Indexed as
Identifiers
26511999What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.