Trial reportHernia : the journal of hernias and abdominal wall surgery2016
Prophylactic mesh placement to prevent parastomal hernia, early results of a prospective multicentre randomized trial.
Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 8 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Pooled it
- Comparison of different mesh placement techniques for parastomal hernia repair: an updated systematic review and network meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Use of prophylactic mesh to prevent parastomal hernia formation: a systematic review, meta-analysis and network meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Effects of different mesh materials on complications after prophylactic placement for stoma formation: a systematic review and network meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Complications of preventive loop ileostomy versus colostomy: a meta-analysis, trial sequential analysis, and systematic review.BMC surgery · 2023Pooled it
- Prophylactic Mesh for Prevention of Parastomal Hernia Following End Colostomy: an Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Pooled it
- Prosthetic mesh placement for the prevention of parastomal herniation.The Cochrane database of systematic reviews · 2018Pooled it
- European Hernia Society guidelines on prevention and treatment of parastomal hernias.Hernia : the journal of hernias and abdominal wall surgery · 2018Guideline
- Extraperitonealization of the ileal conduit decreases the risk of parastomal hernia: A single-center, randomized clinical trial.Cell reports. Medicine · 2024Trial
- Quality of life after end colostomy without mesh and with prophylactic synthetic mesh in sublay position: one-year results of the STOMAMESH trial.International journal of colorectal disease · 2019Trial
- Use of Prophylactic Mesh When Creating a Colostomy Does Not Prevent Parastomal Hernia: A Randomized Controlled Trial-STOMAMESH.Annals of surgery · 2019Trial
- A novel retro-muscular Sugarbaker technique for parastomal hernia prevention in end colostomy: combination of laparoscopic posterior component separation and extraperitoneal bowel pull-through-a prospective, single-arm study using the IDEAL framework.Techniques in coloproctology · 2026Article
- The revisional burden of colostomy: a temporal analysis of risk, patterns, and survival.Techniques in coloproctology · 2026Article
- Systematic review and meta-analysis comparing extraperitoneal and transperitoneal routes of colostomy-related complications.World journal of gastrointestinal surgery · 2025Article
- Prophylactic Mesh Reinforcement for Non-Midline Incisions: A Systematic Review.HCA healthcare journal of medicine · 2024Review
- Update Systematic Review, Meta-Analysis and GRADE Assessment of the Evidence on Parastomal Hernia Prevention-A EHS, ESCP and EAES Collaborative Project.Journal of abdominal wall surgery : JAWS · 2023Article
- EHS Rapid Guideline: Evidence-Informed European Recommendations on Parastomal Hernia Prevention-With ESCP and EAES Participation.Journal of abdominal wall surgery : JAWS · 2023Article
- Article
- A technique for laparoscopic extraperitoneal colostomy with an intact posterior sheath of rectus.BMC surgery · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeParastomal hernia (PSH) is a common complication after colostomy formation. Recent studies indicate that mesh implantation during formation of a colostomy might prevent a PSH. To determine if placement of a retromuscular mesh at the colostomy site is a feasible, safe and effective procedure in preventing a parastomal hernia, we performed a multicentre randomized controlled trial in 11 large teaching hospitals and three university centres in The Netherlands.
methodsAugmentation of the abdominal wall with a retromuscular light-weight polypropylene mesh (Parietene Light™, Covidien) around the trephine was compared with traditional colostomy formation. Patients undergoing elective open formation of a permanent end-colostomy were eligible. 150 patients were randomized between 2010 and 2012. Primary endpoint of the PREVENT trial is the incidence of parastomal hernia. Secondary endpoints are morbidity, pain, quality of life, mortality and cost-effectiveness. This article focussed on the early results of the PREVENT trial and, therefore, operation time, postoperative morbidity, pain, and quality of life were measured.
resultsOutcomes represent results after 3 months of follow-up. A total of 150 patients were randomized. Mean operation time of the mesh group (N = 72) was significantly longer than in the control group (N = 78) (182.6 vs. 156.8 min; P = 0.018). Four (2.7 %) peristomal infections occurred of which one (1.4 %) in the mesh group. No infection of the mesh occurred. Most of the other infections were infections of the perineal wound, equally distributed over both groups. No statistical differences were discovered in stoma or mesh-related complications, fistula or stricture formation, pain, or quality of life.
conclusionsDuring open and elective formation of an end-colostomy, primary placement of a retromuscular light-weight polypropylene mesh for prevention of a parastomal hernia is a safe and feasible procedure. The PREVENT trial is registered at: http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2018 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.