ArticleCancer research and treatment2016
Delay of Treatment Initiation Does Not Adversely Affect Survival Outcome in Breast Cancer.
Article in Cancer research and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of Surgical Delay on Breast Cancer Prognosis: Systematic Review and Meta-analysis.Annals of surgical oncology · 2026Pooled it
- Impact of diagnosis-to-treatment interval on mortality in patients with early-stage breast cancer: a retrospective nationwide Korean cohort.BMC women's health · 2025Article
- Prognosis of Patients with Breast Cancer Following Delayed Diagnosis During the COVID-19 Pandemic: A Real-World Cohort Study.Annals of surgical oncology · 2025Article
- The Magnitude of Delay in Non-metastatic Breast Cancer Treatment in a Tertiary Hospital: an Analysis from 2012 to 2018.Acta medica Philippina · 2025Article
- Five-year survival prognosis of young, middle-aged, and elderly adult female invasive breast cancer patients by clinical and lifestyle characteristics.Breast cancer research and treatment · 2024Article
- Factors Associated with the Nutritional Status of Women with Non-Metastatic Breast Cancer in a Brazilian High Complexity Oncology Center.Nutrients · 2023Observational
- Time interval between breast cancer diagnosis and surgery is associated with disease outcome.Scientific reports · 2023Article
- Benefits versus drawbacks of delaying surgery due to additional consultations in older patients with breast cancer.Cancer reports (Hoboken, N.J.) · 2023Article
- Association of treatment delay and stage with mortality in breast cancer: a nationwide cohort study in Taiwan.Scientific reports · 2022Article
- Breast Cancer Care Timeliness Framework: A Quality Framework for Cancer Control.JCO global oncology · 2022Article
- Prognostic factors and outcomes in women with breast cancer in Slovenia in relation to step-wise implementation of organized screening.PloS one · 2022Article
- Impact of COVID-19 On Breast Cancer Management: A Radiological Prespective from A Tertiary Centre.European journal of breast health · 2021Article
- Management of early-stage breast cancer patients during the coronavirus disease 2019 (COVID-19) pandemic: The experience in China from a surgical standpoint.Journal of Cancer · 2021Review
- "First Do No Harm": Significance of Delays from Diagnosis to Surgery in Patients with Non-metastatic Breast Cancer.World journal of surgery · 2020Article
- Impact of delayed treatment in women diagnosed with breast cancer: A population-based study.Cancer medicine · 2020Article
- The influence on survival of delay in the treatment initiation of screening detected non-symptomatic breast cancer.Scientific reports · 2019Article
- Patient and Care Delays of Breast Cancer in China.Cancer research and treatment · 2019Article
- Reduced Time to Breast Cancer Diagnosis with Coordination of Radiological and Clinical Care.Cureus · 2017Article
- Coordination of radiologic and clinical care reduces the wait time to breast cancer diagnosis.Current oncology (Toronto, Ont.) · 2017Article
- Time interval of neoadjuvant chemotherapy to surgery in breast cancer: how long is acceptable?Gland surgery · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevious studies examining the relationship between time to treatment and survival outcome in breast cancer have shown inconsistent results. The aim of this study was to analyze the overall impact of delay of treatment initiation on patient survival and to determine whether certain subgroups require more prompt initiation of treatment. MATERIALS AND
methodsThis study is a retrospective analysis of stage I-III patients who were treated in a single tertiary institution between 2005 and 2008. Kaplan-Meier survival analysis and Cox proportional hazards regression model were used to evaluate the impact of interval between diagnosis and treatment initiation in breast cancer and various subgroups.
resultsA total of 1,702 patients were included. Factors associated with longer delay of treatment initiation were diagnosis at another hospital, medical comorbidities, and procedures performed before admission for surgery. An interval between diagnosis and treatment initiation as a continuous variable or with a cutoff value of 15, 30, 45, and 60 days had no impact on disease-free survival (DFS). Subgroup analyses for hormone-responsiveness, triple-negative breast cancer, young age, clinical stage, and type of initial treatment showed no significant association between longer delay of treatment initiation and DFS.
conclusionOur results show that an interval between diagnosis and treatment initiation of 60 days or shorter does not appear to adversely affect DFS in breast cancer.
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