Evidence map›Paper›PMID 26511742›Full record

ReviewJournal of clinical microbiology2016

Clinical Utility of Laboratory Detection of Clostridium difficile Strain BI/NAP1/027.

Larry K Kociolek, Dale N Gerding

Abstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. The Strain and the Clinical Outcome ofOpen forum infectious diseases · 2024
    Article
  2. Open forum infectious diseases · 2023
    Article
  3. Rapid visualization ofFrontiers in microbiology · 2023
    Article
  4. Review
  5. Bezlotoxumab for the prevention ofInfection and drug resistance · 2019
    Review
  6. Article
  7. Equivalent Performance of the CobasEuropean journal of microbiology & immunology · 2017
    Article
  8. Article
  9. Article
  10. Detection ofSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Larry K KociolekAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ilinois, USA Northwestern University Feinberg School of Medicine, Chicago, Ilinois, USA lkociolek@luriechildrens.org.
Dale N GerdingEdward Hines, Jr., Veterans Affairs Hospital, Hines, Ilinois, USA Loyola University Chicago Stritch School of Medicine, Maywood, Ilinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium difficile strain BI/NAP1/027 is associated with increased C. difficile infection (CDI) rates and severity, and the efficacy of some CDI therapies may be strain dependent. Although cultured C. difficile isolates can be reliably subtyped by various methods, the long turnaround times, high cost, and limited availability of strain typing preclude their routine use. Nucleic acid amplification tests identify BI/NAP1/027 rapidly from stool, but the emergence of closely related strains compromises test specificity. Although detection of epidemiologically significant pathogens is generally useful for infection control programs, specific data supporting use of rapid detection of BI/NAP1/027 as an infection control tool are still awaited.

Indexed as

Clostridioides difficileClostridium InfectionsFecesGenotypeGenotyping TechniquesHumansMolecular Diagnostic TechniquesPolymerase Chain Reaction

Identifiers

PMID26511742
PMCPMC4702757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.