ArticleG3 (Bethesda, Md.)2015
A Major Locus Controls a Genital Shape Difference Involved in Reproductive Isolation Between Drosophila yakuba and Drosophila santomea.
Article in G3 (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- A developmental atlas of male terminalia across twelve species ofFrontiers in cell and developmental biology · 2024Article
- Resolving between novelty and homology in the rapidly evolving phallus of Drosophila.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023Article
- Evolution of assortative mating following selective introgression of pigmentation genes between twoEcology and evolution · 2022Article
- DrosoPhyla: Resources for Drosophilid Phylogeny and Systematics.Genome biology and evolution · 2021Article
- A morphological trait involved in reproductive isolation between Drosophila sister species is sensitive to temperature.Ecology and evolution · 2021Article
- Article
- An Atlas of Transcription Factors Expressed in Male Pupal Terminalia ofG3 (Bethesda, Md.) · 2019Article
- Genetic basis of species-specific genitalia reveals role in species diversification.Science advances · 2019Article
- Quantifying the extent of morphological homoplasy: A phylogenetic analysis of 490 characters inEvolution letters · 2019Article
- Article
- Genetic and Transgenic Reagents forG3 (Bethesda, Md.) · 2017Article
- Drosophila yakuba mayottensis, a new model for the study of incipient ecological speciation.Fly · 2017Article
- The Genetic Basis of Baculum Size and Shape Variation in Mice.G3 (Bethesda, Md.) · 2016Article
- Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid evolution of genitalia shape, a widespread phenomenon in animals with internal fertilization, offers the opportunity to dissect the genetic architecture of morphological evolution linked to sexual selection and speciation. Most quantitative trait loci (QTL) mapping studies of genitalia divergence have focused on Drosophila melanogaster and its three most closely related species, D. simulans, D. mauritiana, and D. sechellia, and have suggested that the genetic basis of genitalia evolution involves many loci. We report the first genetic study of male genitalia evolution between D. yakuba and D. santomea, two species of the D. melanogaster species subgroup. We focus on male ventral branches, which harm females during interspecific copulation. Using landmark-based geometric morphometrics, we characterized shape variation in parental species, F1 hybrids, and backcross progeny and show that the main axis of shape variation within the backcross population matches the interspecific variation between parental species. For genotyping, we developed a new molecular method to perform multiplexed shotgun genotyping (MSG), which allowed us to prepare genomic DNA libraries from 365 backcross individuals in a few days using little DNA. We detected only three QTL, one of which spans 2.7 Mb and exhibits a highly significant effect on shape variation that can be linked to the harmfulness of the ventral branches. We conclude that the genetic architecture of genitalia morphology divergence may not always be as complex as suggested by previous studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.