ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Increasing Spontaneous Retinal Activity before Eye Opening Accelerates the Development of Geniculate Receptive Fields.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Prolonged Light Exposure Induces Long-Lasting Retinal Wave Plasticity via Retrograde Melanopsin-Dopamine Signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Development of Functional Properties in the Early Visual System: New Appreciations of the Roles of Lateral Geniculate Nucleus.Current topics in behavioral neurosciences · 2022Review
- Balanced Enhancements of Synaptic Excitation and Inhibition Underlie Developmental Maturation of Receptive Fields in the Mouse Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Spontaneous Retinal Waves Can Generate Long-Range Horizontal Connectivity in Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Behavioral states modulate sensory processing in early development.Current sleep medicine reports · 2019Article
- meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays.PLoS computational biology · 2018Article
- Monocular enucleation alters retinal waves in the surviving eye.Neural development · 2018Article
- Activity-dependent development of visual receptive fields.Current opinion in neurobiology · 2017Review
- An evolving view of retinogeniculate transmission.Visual neuroscience · 2017Review
- An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus.eLife · 2016Article
- Glutamatergic Retinal Waves.Frontiers in neural circuits · 2016Review
- Spatiotemporal Features of Retinal Waves Instruct the Wiring of the Visual Circuitry.Frontiers in neural circuits · 2016Review
- The Wiring of Developing Sensory Circuits-From Patterned Spontaneous Activity to Synaptic Plasticity Mechanisms.Frontiers in neural circuitsReview
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Authors and funding
3 authors.
Funding
Abstract
Visually evoked activity is necessary for the normal development of the visual system. However, little is known about the capacity for patterned spontaneous activity to drive the maturation of receptive fields before visual experience. Retinal waves provide instructive retinotopic information for the anatomical organization of the visual thalamus. To determine whether retinal waves also drive the maturation of functional responses, we increased the frequency of retinal waves pharmacologically in the ferret (Mustela putorius furo) during a period of retinogeniculate development before eye opening. The development of geniculate receptive fields after receiving these increased neural activities was measured using single-unit electrophysiology. We found that increased retinal waves accelerate the developmental reduction of geniculate receptive field sizes. This reduction is due to a decrease in receptive field center size rather than an increase in inhibitory surround strength. This work reveals an instructive role for patterned spontaneous activity in guiding the functional development of neural circuits.
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