Trial reportPloS one2015
Effectiveness of a Randomized Controlled Lifestyle Intervention to Prevent Obesity among Chinese Primary School Students: CLICK-Obesity Study.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 16 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- School-based health and nutrition interventions addressing double burden of malnutrition and educational outcomes of adolescents in low- and middle-income countries: A systematic review.Maternal & child nutrition · 2025Pooled it
- Which school-based interventions work better to combat obesity in children? A network meta-analysis.Systematic reviews · 2025Pooled it
- Impact of multi-component school food environment interventions on adiposity and food consumption in children and adolescents: systematic review and meta-analysis.Cadernos de saude publica · 2025Pooled it
- Interventions to prevent obesity in children aged 5 to 11 years old.The Cochrane database of systematic reviews · 2024Pooled it
- Impacts of School Nutrition Interventions on the Nutritional Status of School-Aged Children in Asia: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- School-based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18.The Cochrane database of systematic reviews · 2021Pooled it
- Identifying effective intervention strategies to reduce children's screen time: a systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- How effective are physical activity interventions when they are scaled-up: a systematic review.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Promoting Healthy Eating among Young People-A Review of the Evidence of the Impact of School-Based Interventions.Nutrients · 2020Pooled it
- A systematic review and meta-analysis of the overall effects of school-based obesity prevention interventions and effect differences by intervention components.The international journal of behavioral nutrition and physical activity · 2019Pooled it
- Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019Pooled it
- Environmental interventions to reduce the consumption of sugar-sweetened beverages and their effects on health.The Cochrane database of systematic reviews · 2019Pooled it
- Effectiveness of active school transport interventions: a systematic review and update.BMC public health · 2018Pooled it
- Pooled it
- Strategies for enhancing the implementation of school-based policies or practices targeting risk factors for chronic disease.The Cochrane database of systematic reviews · 2017Pooled it
- Systematic review and meta-analysis of school-based obesity interventions in mainland China.PloS one · 2017Pooled it
- Caregiver App Use and Child Behavioral Adherence in Relation to Obesity-Related Outcomes in an mHealth App-Assisted Childhood Obesity Intervention: Secondary Analysis of a Cluster Randomized Trial.JMIR mHealth and uHealth · 2026Trial
- Effects of a school-based cycling intervention on commuting to school behavior and device-measured activity in Spanish adolescents: the PACO cluster-randomized controlled trial.The international journal of behavioral nutrition and physical activity · 2026Trial
- Trial
- Effect of a Multicomponent Intervention on Lifestyle Factors among Brazilian Adolescents from Low Human Development Index Areas: A Cluster-Randomized Controlled Trial.International journal of environmental research and public health · 2019Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundChildhood obesity has been increasing rapidly worldwide. There is limited evidence for effective lifestyle interventions to prevent childhood obesity worldwide, especially in developing countries like China. The objective of this study was to assess the effectiveness of a school-based multi-component lifestyle childhood obesity prevention program (the CLICK-Obesity study) in Mainland China.
methodsA cluster randomized controlled trial was developed among grade 4 students from 8 urban primary schools (638 students in intervention, 544 as control) in Nanjing City, China. Students were randomly allocated to the control or intervention group at school-level. A one-year multi-component intervention program (classroom curriculum, school environment support, family involvement and fun programs/events) together with routine health education was provided to the intervention group, while the control group received routine health education only. The main outcome variables assessed were changes in body mass index, obesity occurrence, obesity-related lifestyle behaviors and knowledge.
resultsOverall, 1108 (93.7%) of the 1182 enrolled students completed the intervention study. The intervention group had a larger marginal reduction than did the control group in overall mean BMI value (-0.32±1.36 vs. -0.29±1.40, p = 0.09), although this was not significant. Compared with the control group, the intervention group was more likely to decrease their BMI (OR = 1.44, 95%CI = 1.10, 1.87) by 0.5 kg/m2 or above, increase the frequency of jogging/running (OR = 1.55, 95%CI = 1.18, 2.02), decrease the frequency of TV/computer use (OR = 1.41, 95%CI = 1.09, 1.84) and of red meat consumption (OR = 1.50, 95%CI = 1.15, 1.95), change commuting mode to/from school from sedentary to active mode (OR = 2.24, 95%CI = 1.47, 3.40), and be aware of the harm of selected obesity risk factors.
conclusionsThe school-based lifestyle intervention program was practical and effective in improving health behaviors and obesity-related knowledge for children in China. This study provides important policy implications on school-based intervention programs for modifications of obesity-related lifestyles.
trial registrationChinese Clinical Trial Registry ChiCTR-ERC-11001819.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.